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Gastrin Releasing Peptide, Human CAS NO 93755-85-2


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CAS No.:93755-85-2

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

Gastrin Releasing Peptide, Human is a bioactive peptide hormone that plays a critical role in stimulating gastrin release from G-cells in the stomach. This compound is essential for research into gastrointestinal physiology, neuroendocrine signaling, and related pathologies. It is primarily utilized by pharmaceutical R&D teams, academic researchers, and diagnostic manufacturers focused on metabolic disorders and cancer research.

Application

  • Biomedical Research: Used as a key reagent in studies of gastric acid secretion, gut-brain axis communication, and neuropeptide function.
  • Pharmaceutical Development: Serves as a reference standard and active pharmaceutical ingredient (API) in the development of therapies targeting gastrointestinal cancers and ulcers.
  • Diagnostic Assays: Employed in the calibration and development of immunoassays (ELISA, RIA) for measuring gastrin and related hormone levels in clinical samples.
  • Cell Biology Studies: Applied in vitro to investigate receptor binding, signal transduction pathways, and cellular responses in relevant cell lines.
  • Neuroscience Research: Utilized to explore the role of bombesin-like peptides in the central nervous system, including effects on feeding behavior and stress response.

Basic Information

Product Name Gastrin Releasing Peptide, Human
CAS No. 93755-85-2
Molecular Formula C135H220N44O39
Molecular Weight 3080.5 g/mol
Synonyms Human Gastrin-Releasing Peptide; hGRP; GRP (1-27), human; Bombesin-like peptide; Neuromedin C; GRP-27; pGlu-Pro-Leu-Pro-Ala-Gly-Asn-His-Trp-Ala-Val-Gly-His-Leu-Met-NH2; L-pyroglutamyl-L-prolyl-L-leucyl-L-prolyl-L-alanylglycyl-L-asparaginyl-L-histidyl-L-tryptophyl-L-alanyl-L-valylglycyl-L-histidyl-L-leucyl-L-methioninamide
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Quality Control

Our Gastrin Releasing Peptide, Human is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing including HPLC for purity, mass spectrometry (MS) for identity confirmation, and amino acid analysis (AAA). Certificates of Analysis (COA) detailing all specifications are provided to ensure compliance with research and development standards.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. The product is hygroscopic (moisture-sensitive). For long-term storage, consider desiccant and under an inert atmosphere. Allow the vial to equilibrate to room temperature before opening to minimize moisture uptake.

Specification

Item Specification
Appearance White to off-white lyophilized powder
Identification (HPLC/MS) Conforms to reference standard
Purity (HPLC) ≥ 95%
Peptide Content ≥ 80% (by AAA)
Water Content (KF) ≤ 5.0%
Acetate Content (HPLC) ≤ 10.0%
Single Impurity (HPLC) ≤ 2.0%
Bacterial Endotoxins < 10 EU/mg

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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