Description

Methyl (2S)-2-[[(2S)-2-(9H-Fluoren-9-Ylmethoxycarbonylamino)-3-Methylbutanoyl]Amino]-3-Methylbutanoate is a high-purity, protected dipeptide derivative, specifically engineered as a critical building block in advanced organic synthesis. Its primary value lies in providing a precisely controlled chiral center and orthogonal protecting groups, enabling the efficient and scalable production of complex peptide sequences. This compound is essential for researchers and manufacturers in the pharmaceutical and biotechnology sectors, particularly for the development of novel therapeutic peptides, peptidomimetics, and active pharmaceutical ingredients (APIs).

Application

• Solid-Phase Peptide Synthesis (SPPS): A key Fmoc-protected intermediate for the sequential assembly of custom peptide chains in automated synthesizers.
• Pharmaceutical Research & Development: Serves as a crucial precursor in the R&D of peptide-based drugs, hormones, and diagnostic agents.
• Peptidomimetic Design: Used to incorporate non-natural amino acid structures into molecules to enhance stability, bioavailability, and target specificity.
• Combinatorial Chemistry Libraries: Employed in the generation of diverse compound libraries for high-throughput screening against biological targets.
• Bioconjugation: Acts as a specialized linker or spacer molecule in the conjugation of peptides to other biomolecules, polymers, or surfaces.
• Academic & Institutional Research: A fundamental reagent for studies in synthetic organic chemistry, medicinal chemistry, and chemical biology.

Basic Information

Product Name	Methyl (2S)-2-[[(2S)-2-(9H-Fluoren-9-Ylmethoxycarbonylamino)-3-Methylbutanoyl]Amino]-3-Methylbutanoate
CAS No.	93709-91-2
Molecular Formula	C26H32N2O5
Molecular Weight	452.55 g/mol
Synonyms	Fmoc-L-Val-L-Val-OMe; Fmoc-Val-Val-OMe; Methyl N-[(2S)-2-[[(9H-fluoren-9-ylmethoxy)carbonyl]amino]-3-methylbutanoyl]-L-valinate; (2S)-2-[[(2S)-2-[(9H-Fluoren-9-ylmethoxy)formamido]-3-methylbutanoyl]amino]-3-methylbutanoic acid methyl ester; Fmoc-Val-Val-methyl ester; N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-L-valyl-L-valine methyl ester; L-Valine, N-[(9H-fluoren-9-ylmethoxy)carbonyl]-, methyl ester, (2S)-2-[[(2S)-2-[[(9H-fluoren-9-ylmethoxy)carbonyl]amino]-3-methyl-1-oxobutyl]amino]-3-methylbutanoate
EINECS	Contact for details

Quality Control

Our Methyl (2S)-2-[[(2S)-2-(9H-Fluoren-9-Ylmethoxycarbonylamino)-3-Methylbutanoyl]Amino]-3-Methylbutanoate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and chiral integrity, to ensure it meets the exacting standards required for pharmaceutical research and synthesis. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability, consistency, and compliance with your project specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as indicated on the label. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity. Allow the sealed container to equilibrate to room temperature before opening to prevent moisture condensation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.