Description

8-Bromo-3,7-Dihydro-3-Methyl-7-(Phenylmethyl)-1H-Purine-2,6-Dione CAS NO 93703-26-5 is a high-purity, advanced pharmaceutical intermediate belonging to the xanthine derivative class. This compound is valued for its role as a key synthetic precursor in the development of novel therapeutic agents, particularly those targeting adenosine receptors. It is essential for research institutions and pharmaceutical manufacturers engaged in the synthesis of potential drugs for central nervous system (CNS) disorders, cardiovascular conditions, and inflammatory diseases.

Application

• Pharmaceutical Intermediate: A critical building block in the multi-step synthesis of potent adenosine receptor antagonists and other purine-based active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Used extensively in R&D laboratories for structure-activity relationship (SAR) studies and the discovery of new drug candidates.
• Biochemical Tool Compound: Serves as a selective agent in pharmacological assays to study adenosine A1, A2A, A2B, and A3 receptor subtypes.
• Preclinical Development: Employed in the synthesis of compounds for pharmacokinetic, pharmacodynamic, and toxicology studies.
• Academic Research: Utilized in university and institutional labs for fundamental research in neurochemistry and signal transduction pathways.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects under cGMP conditions.

Basic Information

Product Name	8-Bromo-3,7-Dihydro-3-Methyl-7-(Phenylmethyl)-1H-Purine-2,6-Dione
CAS No.	93703-26-5
Molecular Formula	C13H11BrN4O2
Molecular Weight	335.16 g/mol
Synonyms	8-Bromo-3-methyl-7-benzylxanthine; 8-Bromo-3-methyl-7-benzyl-1H-purine-2,6-dione; 8-Bromo-3-methyl-7-benzylxanthine; 8-Bromo-MBX; 8-Br-3-M-7-BzX; 8-Bromo-7-benzyl-3-methylxanthine; 1H-Purine-2,6-dione, 8-bromo-3,7-dihydro-3-methyl-7-(phenylmethyl)-; 8-Bromo-3-methyl-7-(phenylmethyl)xanthine
EINECS	Contact for details

Quality Control

Our 8-Bromo-3,7-Dihydro-3-Methyl-7-(Phenylmethyl)-1H-Purine-2,6-Dione is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production can adhere to cGMP guidelines for pharmaceutical applications upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound may be light-sensitive; prolonged exposure to light should be avoided. Keep container tightly sealed when not in use to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.