Description

Poly (Arginyl-Glycyl-Aspartyl-Threonine) is a synthetic peptide polymer designed to mimic the cell-binding domain of fibronectin. This compound is crucial for applications requiring specific cell adhesion and signaling, as it contains the RGD-Threonine motif, a key sequence recognized by integrin receptors. It is primarily utilized by researchers and manufacturers in the fields of biomaterials, tissue engineering, and advanced drug delivery systems to enhance biocompatibility and direct cellular responses.

Application

• Biomaterial Coating: Used to functionalize surfaces of medical implants, scaffolds, and diagnostic devices to promote specific cell attachment and integration.
• Tissue Engineering: Incorporated into hydrogels and 3D matrices to create bioactive environments that guide cell growth, differentiation, and tissue formation.
• Drug Delivery Systems: Serves as a targeting ligand or a component of nanoparticle coatings to enhance site-specific delivery and cellular uptake of therapeutic agents.
• Cell Culture Research: Applied as a substrate coating to study integrin-mediated cell adhesion, migration, and signaling pathways in vitro.
• Bioink Formulation: An additive for advanced bioinks used in 3D bioprinting to improve the printability and biological functionality of constructed tissues.
• Diagnostic Assays: Utilized in the development of biosensors and assay platforms where controlled cell adhesion is required for detection mechanisms.

Basic Information

Product Name	Poly (Arginyl-Glycyl-Aspartyl-Threonine)
CAS No.	93675-01-5
Molecular Formula	(C19H32N8O8)n
Molecular Weight	Contact for details
Synonyms	Poly(RGD-Threonine); Poly(Arg-Gly-Asp-Thr); RGD-Thr Polymer; Poly(RGD-T) Peptide; Fibronectin Cell-Binding Domain Mimetic; Poly(RGD-Thr); Poly(RGD-Threonine) Peptide; Poly(RGD-Thr) Polymer
EINECS	Contact for details

Quality Control

Our Poly (Arginyl-Glycyl-Aspartyl-Threonine) is produced under stringent quality management systems. Each batch undergoes comprehensive analytical testing, including sequence verification, purity assessment, and molecular weight distribution analysis, to ensure consistency and performance for critical research and development applications. Certificates of Analysis (COA) detailing specific batch results are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a freezer at -20°C or below. This material is hygroscopic (moisture-sensitive). Allow the sealed container to equilibrate to room temperature before opening to minimize moisture absorption. For long-term storage, consider desiccant or under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95%
Amino Acid Composition	Conforms to theoretical values
Water Content (KF)	≤ 5.0 %
Solubility	Soluble in water or aqueous buffers

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.