Description

Arginyl-Glycyl-Aspartyl-Alanine CAS NO 93674-98-7 is a synthetic tetrapeptide sequence derived from the cell adhesion motif found in fibronectin and other extracellular matrix proteins. This compound is a critical research tool for studying integrin-mediated cell adhesion, signaling, and migration processes. It is primarily utilized by researchers and developers in the life sciences, pharmaceutical, and biomedical engineering sectors for applications in cell culture, drug discovery, and biomaterial development.

Application

• Cell Adhesion Studies: Used as a coating substrate to promote specific integrin-mediated cell attachment in vitro.
• Biomaterial Functionalization: Incorporated into hydrogels, scaffolds, and medical device coatings to enhance biocompatibility and cellular integration.
• Drug Discovery Screening: Serves as a reference compound or competitive inhibitor in assays targeting integrin receptors (e.g., αvβ3, α5β1).
• Angiogenesis Research: Applied in studies investigating endothelial cell proliferation and tube formation.
• Neuroscience Research: Utilized to study neuronal cell adhesion, outgrowth, and synapse formation.
• Diagnostic Development: Potential use in the development of biosensors or diagnostic kits targeting specific cell surface integrins.

Basic Information

Product Name	Arginyl-Glycyl-Aspartyl-Alanine
CAS No.	93674-98-7
Molecular Formula	C18H32N8O8
Molecular Weight	488.50 g/mol
Synonyms	Arg-Gly-Asp-Ala; RGD-Alanine; RGD-Ala; RGDA; Fibronectin Adhesion-promoting Peptide (RGD-Ala); Adhesion Peptide RGD-Ala; H-Arg-Gly-Asp-Ala-OH; Tetrapeptide RGD-Ala
EINECS	Contact for details

Quality Control

Our Arginyl-Glycyl-Aspartyl-Alanine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, MS for identity confirmation, and amino acid analysis. Certificates of Analysis (COA) detailing all specifications are provided to ensure traceability and compliance with research-grade standards.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to prevent condensation and moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 95.0%
Single Impurity (HPLC)	≤ 2.0%
Water Content (KF)	≤ 5.0%
Peptide Content	≥ 80.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.