Description

Nemonapride is a potent and selective dopamine D2 and D3 receptor antagonist belonging to the benzamide class of antipsychotic agents. This high-purity compound is critical for pharmaceutical research and development, particularly in the study of neuropsychiatric disorders. It is primarily utilized by researchers and manufacturers in the pharmaceutical and biotechnology sectors for developing novel therapeutic agents and conducting advanced pharmacological studies.

Application

• Pharmaceutical Reference Standard: Serves as a certified reference material (CRM) for quality control and analytical method development in drug manufacturing.
• Neuroscience Research: Used as a selective pharmacological tool to study dopamine receptor function, signaling pathways, and their role in conditions like schizophrenia and psychosis.
• Preclinical Drug Development: Employed in animal model studies to investigate the efficacy, pharmacokinetics, and safety profile of antipsychotic mechanisms.
• Biochemical Assays: Acts as a key ligand in receptor binding assays and high-throughput screening (HTS) to identify new drug candidates.
• Metabolite Identification: Used in metabolism and pharmacokinetics (DMPK) studies to identify and characterize potential metabolites.

Basic Information

Product Name	Nemonapride
CAS No.	93664-94-9
Molecular Formula	C21H26ClN3O2
Molecular Weight	387.91 g/mol
Synonyms	YM-09151-2; Emonapride; (3S)-3-[5-Chloro-2-methoxy-4-(methylamino)benzoyl]-1-ethyl-2-methylindole; 1-Ethyl-2-methyl-3-[(2S)-5-chloro-2-methoxy-4-(methylamino)benzoyl]indole; N-Methyl-2-chloro-5-methoxy-4-[(1-ethyl-2-methyl-1H-indol-3-yl)carbonyl]aniline; YM 09151-2
EINECS	Contact for details

Quality Control

Our Nemonapride is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research applications. Each lot undergoes comprehensive analytical testing, including identity confirmation by spectroscopic methods (IR, NMR), purity determination by HPLC, and residual solvent analysis. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all test results against established in-house specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.