Description

cis-Thiothixene is a high-purity organic compound belonging to the thioxanthene class, specifically the cis-isomer of thiothixene. This compound is of significant interest in advanced pharmaceutical research and development due to its specific structural configuration. It serves as a critical intermediate or reference standard for organizations engaged in the synthesis and analysis of neuroactive agents. Industries requiring precise chemical building blocks for life science applications will find this material essential for their development pipelines.

Application

• Pharmaceutical Intermediate: Serves as a key synthetic precursor in the research and development of active pharmaceutical ingredients (APIs) with neurological activity.
• Reference Standard: Used as an analytical standard in quality control laboratories for method development, validation, and impurity profiling.
• Biochemical Research: Employed in academic and industrial research to study structure-activity relationships (SAR) and receptor binding mechanisms.
• Process Chemistry: Utilized in scaling up synthetic routes and optimizing manufacturing processes for related therapeutic compounds.
• Metabolite Studies: Acts as a starting material or reference compound in the synthesis and identification of drug metabolites for pharmacokinetic studies.

Basic Information

Product Name	cis-Thiothixene
CAS No.	3313-26-6
Molecular Formula	C₂₃H₂₉N₃O₂S₂
Molecular Weight	443.62 g/mol
Synonyms	(Z)-Thiothixene; cis-Tiotixene; (9Z)-N,N-Dimethyl-9-[3-(4-methylpiperazin-1-yl)propylidene]thioxanthene-2-sulfonamide; (Z)-N,N-Dimethyl-9-[3-(4-methyl-1-piperazinyl)propylidene]thioxanthene-2-sulfonamide; Navane (cis-isomer); P-4657B; Compound 3313-26-6
EINECS	Contact for details

Quality Control

Our cis-Thiothixene is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including identity confirmation by spectroscopic methods and purity determination by chromatographic techniques. Certificates of Analysis (COA) detailing all test results are provided and can be tailored to meet specific client or pharmacopeial requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Maximum Unknown Impurity	≤ 0.5%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.