Description

Spiroxatrine CAS NO 1054-88-2 is a selective serotonin (5-HT1A) receptor antagonist with significant research applications in neuropharmacology. Its primary value lies in its utility as a precise biochemical tool for studying serotonergic pathways and receptor mechanisms. This compound is essential for pharmaceutical R&D laboratories, academic research institutions, and chemical suppliers serving the life sciences sector.

Application

• Pharmacological Research: Used as a reference standard and active agent in studies investigating serotonin (5-HT1A) receptor function and antagonism.
• Neuroscience Studies: A critical tool for exploring the role of serotonergic systems in behavior, anxiety, depression, and other CNS disorders.
• Drug Discovery & Development: Serves as a lead compound or biochemical probe in the screening and development of new central nervous system (CNS) therapeutics.
• Academic & Clinical Research: Employed in university and hospital laboratories for fundamental and translational research into neurotransmitter systems.
• Reference Standard: Used in analytical chemistry for method development, calibration, and quality control in pharmaceutical analysis.
• Biochemical Assay Development: Integral to creating and validating in vitro receptor binding assays and functional cellular tests.

Basic Information

Product Name	Spiroxatrine
CAS No.	1054-88-2
Molecular Formula	C21H23N3O2
Molecular Weight	349.43 g/mol
Synonyms	Spiroxatrine; 8-[4-(4-Fluorophenyl)-4-oxobutyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one; 1-Phenyl-8-[4-(4-fluorophenyl)-4-oxobutyl]-1,3,8-triazaspiro[4.5]decan-4-one; Spiroxatrin; Spiroxatrinum; Spiroxatrine Hydrochloride (salt form); 5-HT1A Receptor Antagonist; BRN 0090853
EINECS	Contact for details

Quality Control

Our Spiroxatrine is produced and handled under strict quality management protocols to ensure batch-to-batch consistency and reliability for research purposes. Each lot undergoes comprehensive analytical testing, including identification, purity assay, and impurity profiling. A Certificate of Analysis (COA) detailing all test results is provided with every shipment to support your research integrity and documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (typically 15-25°C). Keep the container sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Residual Solvents (GC)	Complies with ICH guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.