Description

Chlorprothixene Hydrochloride is a potent thioxanthene derivative with antipsychotic and neuroleptic properties. This active pharmaceutical ingredient (API) is critical for the formulation of medications used in psychiatric care. It is primarily required by pharmaceutical manufacturers and research institutions engaged in the development and production of neuropsychiatric therapeutics. Consistent quality and reliable supply are paramount for ensuring the efficacy and safety of the final drug products.

Application

• Pharmaceutical Active Ingredient (API): Primary use in the manufacture of antipsychotic and neuroleptic medications.
• Reference Standard: Serves as a certified reference material (CRM) for quality control and analytical method development in pharmaceutical labs.
• Research & Development: Used in preclinical and clinical studies to investigate mechanisms of action and therapeutic efficacy for central nervous system disorders.
• Formulation Development: Essential for developing various dosage forms such as tablets, capsules, or injectables.
• Pharmacopoeial Testing: Employed in laboratories for compliance testing against pharmacopoeial monographs (e.g., USP, EP).

Basic Information

Product Name	Chlorprothixene Hydrochloride
CAS No.	6469-93-8
Molecular Formula	C18H19ClN2OS • HCl
Molecular Weight	367.73 g/mol
Synonyms	Chlorprothixene HCl; Taractan; Truxal; Cloxan; 2-Chloro-9-(3-dimethylaminopropylidene)thioxanthene Hydrochloride; (Z)-2-Chloro-N,N-dimethyl-9H-thioxanthene-9-propanamine Hydrochloride; NSC-71948; CPX HCl
EINECS	229-284-5

Quality Control

Our Chlorprothixene Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure it meets high-purity standards suitable for pharmaceutical use. We provide detailed Certificates of Analysis (COA) that include results for identity, assay, purity, and specified impurities, referencing pharmacopoeial methods where applicable.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed in a dry environment away from direct light exposure to maintain stability and potency.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Related Substances (HPLC)	Total impurities ≤ 2.0%
Individual Unknown Impurity	≤ 0.10%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.