Description

Fluphenazine Hydrochloride is a high-purity pharmaceutical active ingredient (API) belonging to the phenothiazine class of antipsychotic agents. Its primary value lies in its potent dopamine receptor antagonism, making it a critical component in the formulation of long-acting injectable and oral neuroleptic medications. This compound is essential for manufacturers in the global pharmaceutical industry developing treatments for psychiatric conditions such as schizophrenia and other psychotic disorders.

Application

• Pharmaceutical API: Primary active ingredient in the manufacture of antipsychotic medications.
• Long-Acting Injectable Formulations: Key component in depot injection preparations for sustained therapeutic release.
• Oral Dosage Forms: Used in the production of tablets and capsules for the management of chronic psychotic disorders.
• Research & Development: Reference standard and building block in neuropharmacology research and new drug development.
• Generic Drug Manufacturing: Sourcing for the production of bioequivalent generic antipsychotic drugs.
• Hospital Formulary Preparations: Used in compounding pharmacies for specific patient dosage requirements.

Basic Information

Product Name	Fluphenazine Hydrochloride
CAS No.	146-56-5
Molecular Formula	C22H26F3N3OS • HCl
Molecular Weight	477.98 g/mol
Synonyms	Fluphenazine HCl; 4-[3-[2-(Trifluoromethyl)-10H-phenothiazin-10-yl]propyl]-1-piperazineethanol dihydrochloride; Prolixin Hydrochloride; Anatensol Hydrochloride; Permitil Hydrochloride; Flufenazina Hydrochloride; Fluphenazini Hydrochloridum; SQ 4918
EINECS	205-683-0

Quality Control

Our Fluphenazine Hydrochloride is manufactured under strict quality management systems. Each batch is tested to ensure it meets stringent specifications for identity, purity, and potency, aligning with pharmacopeial standards. A comprehensive Certificate of Analysis (COA) detailing results for assay, related substances, residual solvents, and microbiological attributes is provided with every shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White or almost white, crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Individual impurity: ≤ 0.5%; Total impurities: ≤ 1.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.