Description

Penfluridol is a potent, long-acting diphenylbutylpiperidine derivative belonging to the class of typical antipsychotic agents. Its primary value lies in its extended duration of action, which is critical for managing chronic psychiatric conditions with improved patient compliance. This high-purity active pharmaceutical ingredient (API) is essential for pharmaceutical manufacturers and research institutions developing neuroleptic medications and conducting advanced pharmacological studies. Penfluridol CAS NO 26864-56-2 is supplied under stringent quality control to meet the exacting standards of the global pharmaceutical industry.

Application

• Pharmaceutical API: Primary use as the active ingredient in the formulation of long-acting oral antipsychotic medications.
• Neuroleptic Drug Development: Key intermediate in research and development of new antipsychotic drugs targeting dopamine receptors.
• Pharmacological Research: Used in preclinical and clinical studies to understand the mechanisms of action and pharmacokinetics of butyrophenone derivatives.
• Reference Standard: Serves as a high-purity chemical reference standard for quality control and analytical testing in pharmaceutical laboratories.
• Chemical Synthesis: Utilized as a building block or intermediate in the organic synthesis of related psychoactive compounds.

Basic Information

Product Name	Penfluridol
CAS No.	26864-56-2
Molecular Formula	C28H27ClF5NO
Molecular Weight	523.97 g/mol
Synonyms	1-[4,4-Bis(4-fluorophenyl)butyl]-4-[4-chloro-3-(trifluoromethyl)phenyl]-4-piperidinol; Semap; Flupidol; Longoran; Micefal; R-16341; R-16,341; 4-[4-Chloro-3-(trifluoromethyl)phenyl]-1-[4,4-bis(4-fluorophenyl)butyl]-4-piperidinol
EINECS	Contact for details

Quality Control

Our Penfluridol is manufactured and tested to meet the rigorous standards required for pharmaceutical active ingredients. Quality is assured through a comprehensive battery of analytical tests, including identification, assay, and impurity profiling. We adhere to cGMP (current Good Manufacturing Practice) guidelines, and a detailed Certificate of Analysis (COA) is provided with each batch to confirm identity, purity, and compliance with agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a dry environment to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.5%
Related Substances (HPLC)	Total impurities ≤ 1.5% Any single impurity ≤ 0.5%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.