Description

H-Ala-Val-Leu-Oh is a high-purity tripeptide derivative, specifically the C-terminal carboxylic acid form of the sequence Alanine-Valine-Leucine. This compound serves as a critical building block and reference standard in advanced biochemical research and pharmaceutical development. It is essential for researchers and manufacturers in the fields of peptide synthesis, proteomics, and drug discovery who require precise and reliable intermediates.

Application

• Peptide Synthesis Intermediate: Used as a key fragment in the solid-phase or solution-phase synthesis of longer, biologically active peptide chains.
• Pharmaceutical Reference Standard: Acts as a certified reference material (CRM) for quality control and analytical method development in drug manufacturing.
• Biochemical Research: Employed in enzymatic studies, substrate specificity assays, and investigations into protein-protein interactions.
• Proteomics & Mass Spectrometry: Serves as a calibrant or standard in LC-MS/MS workflows for peptide identification and quantification.
• Cosmetic Peptide Development: Investigated for potential use as a bioactive ingredient in advanced skincare formulations.
• Academic & Institutional Research: Provides a well-defined compound for university and laboratory studies in chemistry and life sciences.

Basic Information

Product Name	H-Ala-Val-Leu-Oh
CAS No.	93414-38-1
Molecular Formula	C14H27N3O4
Molecular Weight	301.38 g/mol
Synonyms	Ala-Val-Leu; A-V-L-OH; L-Alanyl-L-valyl-L-leucine; H-Ala-Val-Leu-OH; Alanine-Valine-Leucine; Tripeptide A-V-L; AVL; N-(L-Alanyl)-L-valyl-L-leucine
EINECS	Contact for details

Quality Control

Every batch of H-Ala-Val-Leu-Oh is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, MS, and NMR, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing batch-specific results are provided and available upon request, supporting compliance with research and cGMP guidelines where applicable.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.