Description

Fibrinogen Bbeta (1-21) CAS NO 93334-58-8 is a defined peptide fragment derived from the Bbeta chain of human fibrinogen. This high-purity synthetic peptide is a critical research tool for studying the structure, function, and proteolytic processing of fibrinogen in hemostasis and thrombosis. It is essential for scientists and developers in pharmaceutical research, diagnostic assay development, and biochemical studies requiring precise molecular probes.

Application

• Biochemical Research: Used as a specific substrate or inhibitor in enzymatic studies related to fibrinogen processing, particularly for thrombin and other coagulation factor assays.
• Diagnostic Development: Serves as a key antigen or calibrator in the development of immunoassays (ELISA) for detecting fibrinogen degradation products or related antibodies.
• Pharmaceutical R&D: Employed in structure-activity relationship (SAR) studies to design novel antithrombotic or hemostatic agents targeting fibrinogen interactions.
• Quality Control Reference: Acts as a reference standard for the quality control of therapeutic proteins or diagnostic kits derived from or targeting fibrinogen.
• Cell Biology Studies: Utilized to investigate cell adhesion and signaling pathways mediated by fibrinogen fragments.

Basic Information

Product Name	Fibrinogen Bbeta (1-21)
CAS No.	93334-58-8
Molecular Formula	C106H165N31O33
Molecular Weight	~2350.6 g/mol
Synonyms	Fibrinogen Bβ Chain (1-21); Human Fibrinogen Bβ(1-21) Peptide; Bbeta1-21; Fibrinopeptide B (1-21); FpB (1-21); H-FpB (1-21); FGB (1-21); Synthetic Fibrinogen Fragment
EINECS	Contact for details

Quality Control

Our Fibrinogen Bbeta (1-21) is manufactured under strict quality systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity verification, mass spectrometry (MS) for identity confirmation, and amino acid analysis (AAA). We provide a comprehensive Certificate of Analysis (COA) with each shipment, detailing all test results to ensure the material meets the stringent requirements for research and diagnostic applications.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC & MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Peptide Content	≥ 80% (by AAA)
Water Content (KF)	≤ 5.0%
Solubility	Soluble in water or dilute acetic acid

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.