Description

Bovine Parathyroid Hormone (1-41) is a bioactive peptide fragment representing the N-terminal region of the native parathyroid hormone. This specific sequence is critical for its biological activity, primarily binding to the PTH1 receptor to regulate calcium and phosphate homeostasis. It serves as a vital research and reference standard for scientists in endocrinology, bone metabolism, and pharmaceutical development. Key industrial users include biochemical manufacturers, diagnostic kit producers, and academic research institutions focusing on metabolic bone diseases.

Application

• Biochemical Research: Used as a high-purity reference standard in studies of calcium metabolism, bone biology, and renal function.
• Pharmaceutical Development: Serves as a key intermediate or active pharmaceutical ingredient (API) in the development of therapies for osteoporosis and hypoparathyroidism.
• Diagnostic Manufacturing: Employed in the production of calibration standards and controls for immunoassays measuring PTH levels in clinical settings.
• Cell Culture & Signal Transduction: Applied in in vitro studies to stimulate cAMP production and investigate PTH receptor signaling pathways.
• Antibody Production: Acts as an immunogen for generating specific antibodies used in research and diagnostic applications.
• Quality Control: Utilized by manufacturers as a system suitability standard to validate analytical methods for related peptide products.

Basic Information

Product Name	Bovine Parathyroid Hormone (1-41)
CAS No.	93050-48-7
Molecular Formula	C₂₁₀H₃₄₄N₆₀O₆₃S₂
Molecular Weight	4827.4 g/mol
Synonyms	Parathyroid Hormone (1-41), bovine; PTH (1-41); bPTH(1-41); Parathyrin (1-41); NSC 106983; Bovine Parathormone fragment 1-41; Parathyroid hormone bovine 1-41
EINECS	Contact for details

Quality Control

Our Bovine Parathyroid Hormone (1-41) is manufactured and tested under strict quality management systems. Each batch undergoes comprehensive analytical characterization to ensure identity, purity, and biological activity. Certificates of Analysis (COA) are provided, detailing results from tests including HPLC purity, peptide content, amino acid analysis, and mass spectrometry. We support compliance with relevant guidelines for research and pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. The product is hygroscopic (moisture-sensitive). For long-term storage, consider desiccant and under an inert atmosphere. Allow the vial to equilibrate to room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC)	Retention time corresponds to reference standard
Identification (MS)	Molecular weight confirmed by Mass Spectrometry
Purity (HPLC)	≥ 95.0%
Peptide Content	≥ 80.0% (by amino acid analysis)
Water Content (KF)	≤ 5.0%
Biological Activity	Stimulates cAMP production in suitable cell lines (Data on COA)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.