Description

α-(3-Methyl-3-Buten-1-Ynyl)-α-Hydroxycyclopentaneacetic Acid 3-Quinuclidinyl Ester is a high-purity synthetic intermediate of significant interest in advanced pharmaceutical research and development. This compound serves as a critical building block for the synthesis of novel active pharmaceutical ingredients (APIs) with targeted therapeutic effects. It is primarily utilized by research institutions, contract development and manufacturing organizations (CDMOs), and pharmaceutical companies engaged in the discovery of new drug candidates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex molecules for drug discovery programs.
• Neurological Research: Used in the development of compounds targeting neurological pathways, given its quinuclidinyl ester moiety.
• Medicinal Chemistry: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization.
• Contract Manufacturing: Supplied to CDMOs for the cGMP production of clinical trial materials and commercial APIs.
• Academic Research: Utilized in university and institutional labs for chemical biology and pharmacological studies.
• Process Development: Employed in the scale-up and optimization of synthetic routes for new chemical entities (NCEs).

Basic Information

Product Name	α-(3-Methyl-3-Buten-1-Ynyl)-α-Hydroxycyclopentaneacetic Acid 3-Quinuclidinyl Ester
CAS No.	92955-92-5
Molecular Formula	C17H23NO3
Molecular Weight	289.37 g/mol
Synonyms	3-Quinuclidinyl α-(3-methyl-3-buten-1-yn-1-yl)-α-hydroxycyclopentaneacetate; α-Hydroxy-α-(3-methyl-3-buten-1-ynyl)cyclopentaneacetic Acid 3-Quinuclidinyl Ester; 3-Quinuclidinol, ester with α-(3-methyl-3-buten-1-ynyl)-α-hydroxycyclopentaneacetic acid; (αR)-α-(3-Methyl-3-buten-1-yn-1-yl)-α-hydroxycyclopentaneacetic acid 3-quinuclidinyl ester; CAS 92955-92-5
EINECS	Contact for details

Quality Control

Our α-(3-Methyl-3-Buten-1-Ynyl)-α-Hydroxycyclopentaneacetic Acid 3-Quinuclidinyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We support development needs with custom purity grades and can align with cGMP standards for advanced pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider inert atmosphere conditions to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.