Description

Riluzole is a benzothiazole derivative and a potent neuroprotective agent that functions as a glutamate antagonist. This compound is of critical importance in pharmaceutical research and development, particularly for its role in modulating excitatory neurotransmission. It is primarily required by pharmaceutical manufacturers and research institutions focused on developing treatments for neurological conditions.

Application

• Active Pharmaceutical Ingredient (API): Serves as the key therapeutic component in prescription medications.
• Neurological Research: Used extensively in preclinical and clinical studies targeting amyotrophic lateral sclerosis (ALS) and other neurodegenerative diseases.
• Reference Standard: Employed as a high-purity standard in analytical laboratories for quality control and method validation.
• Mechanistic Studies: A vital tool for investigating glutamatergic pathways and neuronal excitotoxicity.
• Formulation Development: Utilized in the development of various dosage forms, including tablets and oral suspensions.
• Biochemical Assays: Acts as a specific inhibitor in enzymatic and receptor-binding assays related to glutamate signaling.

Basic Information

Item	Detail
Product Name	Riluzole
CAS No.	1744-22-5
Molecular Formula	C8H5F3N2OS
Molecular Weight	234.20 g/mol
Synonyms	2-Amino-6-(trifluoromethoxy)benzothiazole; Rilutek; PK 26124; RP 54274; 6-(Trifluoromethoxy)-2-benzothiazolamine; 2-Benzothiazolamine, 6-(trifluoromethoxy)-; RP54274
EINECS	217-122-9

Quality Control

Our Riluzole is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure it meets stringent pharmaceutical-grade specifications, including identity, purity, and impurity profile verification. A Certificate of Analysis (COA) documenting all test results is provided with every shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	98.0% - 102.0%
Related Substances (HPLC)	Total impurities ≤ 1.0% Any individual impurity ≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm
Sulfated Ash	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.