Description

Cabergoline is a potent, long-acting dopamine D2 receptor agonist belonging to the ergoline class of compounds. This high-purity active pharmaceutical ingredient (API) is critical for the formulation of effective and reliable pharmaceutical treatments. It is primarily required by pharmaceutical manufacturers and research institutions engaged in the development and production of specialized therapeutics.

Application

• Pharmaceutical API: Primary use as the active ingredient in prescription medications for endocrine disorders.
• Hyperprolactinemia Treatment: Formulation of drugs used to manage conditions associated with high prolactin levels, such as prolactinomas.
• Parkinson's Disease Therapy: Utilized as an adjunctive treatment in managing symptoms of Parkinson's disease.
• Research & Development: Serves as a critical reference standard and building block in neurological and endocrine research.
• Veterinary Medicine: Potential application in veterinary pharmaceuticals for similar endocrine conditions in animals.
• Controlled-Release Formulations: Suitable for development into long-acting dosage forms due to its extended half-life.

Basic Information

Product Name	Cabergoline
CAS No.	81409-90-7
Molecular Formula	C26H37N5O2
Molecular Weight	451.61 g/mol
Synonyms	Cabergoline; FCE-21336; 1-[(6-Allylergolin-8β-yl)carbonyl]-1-[3-(dimethylamino)propyl]-3-ethylurea; Dostinex (brand name); Cabaser (brand name); Galastop (veterinary brand); (8β)-N-[3-(Dimethylamino)propyl]-N-[(ethylamino)carbonyl]-6-(2-propen-1-yl)ergoline-8-carboxamide
EINECS	Contact for details

Quality Control

Our Cabergoline is manufactured under strict quality management systems to ensure it meets the stringent requirements for pharmaceutical actives. Each batch undergoes comprehensive analytical testing, including identification, purity assay, and impurity profiling via HPLC and related substances tests. Certificates of Analysis (COA) are provided, detailing compliance with in-house specifications developed in alignment with ICH guidelines. We support audits and can provide documentation for regulatory submissions.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); ensure the container is kept tightly sealed in a low-humidity environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single unknown impurity ≤ 0.5%
Water (KF)	≤ 1.0% w/w
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.