Description

S-(-)-Lisuride is a high-purity, stereochemically defined ergoline derivative, recognized for its potent dopaminergic and serotonergic receptor activity. This compound is critical for advanced pharmaceutical research and development, particularly in the study of neurological pathways and receptor pharmacology. It is primarily utilized by research institutions, pharmaceutical R&D departments, and fine chemical manufacturers engaged in the synthesis of novel therapeutic agents for central nervous system disorders.

Application

• Pharmaceutical Reference Standard: Serves as a certified analytical standard for quality control and method validation in drug development and manufacturing.
• Neurological Research: A key tool compound for in vitro and in vivo studies targeting dopamine D2 and serotonin 5-HT1A/2A receptors.
• Active Pharmaceutical Ingredient (API) Intermediate: Used in the synthetic pathway for developing potential therapeutics for Parkinson's disease, migraine, and other neurological conditions.
• Biochemical Assay Development: Employed in high-throughput screening (HTS) and binding assays to identify and characterize new receptor ligands.
• Metabolite Studies: Utilized in pharmacokinetic and metabolic pathway research to understand the compound's behavior in biological systems.

Basic Information

Product Name	S-(-)-Lisuride
CAS No.	18016-80-3
Molecular Formula	C₂₀H₂₆N₄O
Molecular Weight	338.45 g/mol
Synonyms	Lisuride; (8β)-N-[((S)-1-Ethyl-2-pyrrolidinyl)methyl]-6-methylergoline-8-carboxamide; Lisenil; Dopergin; Lysenyl; LY-46275; N-0437; Revanil
EINECS	Contact for details

Quality Control

Our S-(-)-Lisuride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification, to ensure it meets the high standards required for research and development. A detailed Certificate of Analysis (COA) providing batch-specific results for identity, purity, and related substances is supplied with every order.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% (S-(-)-enantiomer)
Related Substances (HPLC)	Total impurities ≤2.0%
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.