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R(-)-n-Allylnorapomorphine Hbr CAS NO 18426-17-0
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CAS No.:18426-17-0
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
R(-)-n-Allylnorapomorphine Hbr is a high-purity, enantiomerically pure chemical compound belonging to the aporphine class of alkaloids. This compound is of significant value in advanced pharmaceutical research and development, particularly for its potential as a selective dopamine receptor ligand. It is primarily sought after by research institutions, pharmaceutical companies, and contract development and manufacturing organizations (CDMOs) engaged in neuroscience, neuropharmacology, and the development of central nervous system (CNS) therapeutics.
Application
- Pharmaceutical Reference Standard: Serves as a certified reference material (CRM) for analytical method development, validation, and quality control in drug manufacturing.
- Neuroscience Research: Used as a critical tool compound in vitro and in vivo studies to investigate dopamine D1 and D2 receptor pharmacology and signaling pathways.
- Drug Discovery & Development: Acts as a key intermediate or active pharmaceutical ingredient (API) precursor in the synthesis of novel therapeutic agents targeting Parkinson's disease and related neurological disorders.
- Biochemical Assays: Employed in high-throughput screening (HTS) and receptor binding assays to identify and characterize new drug candidates.
- Academic Research: Utilized in university and institutional labs for fundamental studies on the structure-activity relationships (SAR) of aporphine derivatives.
Basic Information
| Product Name | R(-)-n-Allylnorapomorphine Hbr |
| CAS No. | 18426-17-0 |
| Molecular Formula | C19H21NO2 • HBr |
| Molecular Weight | 376.29 g/mol |
| Synonyms | (-)-N-Allylnorapomorphine Hydrobromide; R-(-)-N-Allylnorapomorphine HBr; (R)-(-)-11-Allyl-1,2,3,4,4a,5,6,10b-octahydro-6-hydroxy-2-methylbenzo[f]quinolin-3-ol Hydrobromide; 11-Allyl-6aβ-aporphine-10,11-diol Hydrobromide; R(-)-N-Allyl-N-norapomorphine Hydrobromide; R(-)-Allylnorapomorphine HBr |
| EINECS | Contact for details |
Quality Control
Every batch of R(-)-n-Allylnorapomorphine Hbr is manufactured and tested under strict quality management systems. Our products undergo rigorous analytical testing, including chiral HPLC, to ensure high enantiomeric purity and chemical identity. Certificates of Analysis (COA) detailing purity, impurities, and other critical parameters are provided with each shipment to support your research and regulatory requirements.
Storage
Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a desiccated environment to maintain stability and purity.
Specification
| Item | Specification |
|---|---|
| Appearance | White to off-white powder |
| Identification (IR) | Conforms to structure |
| Identification (HPLC) | Conforms to reference |
| Assay (HPLC) | ≥98.0% |
| Chiral Purity (HPLC) | ≥99.0% ee |
| Loss on Drying | ≤1.0% |
| Residue on Ignition | ≤0.1% |
| Heavy Metals | ≤20 ppm |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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