Description

Benztropine Mesylate is a synthetic anticholinergic agent belonging to the class of tropane alkaloids. This compound is a critical active pharmaceutical ingredient (API) valued for its potent muscarinic receptor antagonism. It is primarily utilized in the pharmaceutical industry for the formulation of medications targeting neurological disorders. Benztropine Mesylate CAS NO 132-17-2 is supplied to meet the stringent quality requirements of global pharmaceutical manufacturers and research institutions.

Application

• Pharmaceutical API: Primary use as the active ingredient in prescription medications for the treatment of Parkinson's disease and drug-induced extrapyramidal symptoms.
• Neurological Research: Used as a reference standard and tool compound in preclinical studies investigating cholinergic pathways and movement disorders.
• Formulation Development: Employed in the R&D of various dosage forms, including tablets and injectables, requiring high-purity active ingredients.
• Pharmacopoeial Standards: Serves as a chemical reference substance (CRS) for quality control testing in compliance with pharmacopoeial monographs (e.g., USP, BP).
• Chemical Synthesis: Acts as a key intermediate or starting material for the synthesis of more complex pharmaceutical molecules and derivatives.

Basic Information

Product Name	Benztropine Mesylate
CAS No.	132-17-2
Molecular Formula	C21H25NO·CH4O3S
Molecular Weight	403.53 g/mol
Synonyms	Benzatropine Mesylate; 3α-(Diphenylmethoxy)tropane Methanesulfonate; Cogentin® (brand name); Tropine Benzohydryl Ether Methanesulfonate; Benztropine Methanesulfonate; (3-Endo)-3-(Diphenylmethoxy)-8-methyl-8-azabicyclo[3.2.1]octane Methanesulfonate; 8-Methyl-3α-tropanyl benzilate methanesulfonate; NSC-17788
EINECS	205-054-9

Quality Control

Our Benztropine Mesylate is manufactured under strict quality management systems. It undergoes rigorous analytical testing to ensure compliance with relevant pharmacopoeial standards such as USP and BP. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles, ensuring traceability and reliability for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a low-humidity environment to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to standard
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.