Description

Cholecystokinin (27-32) Amide, Benzoyloxycarbonyl- is a synthetic peptide fragment derived from the C-terminal sequence of the gastrointestinal hormone cholecystokinin (CCK). This compound is a crucial research-grade biochemical tool for studying CCK receptor binding, signal transduction pathways, and the physiological roles of CCK in digestion and satiety. It is primarily utilized by pharmaceutical R&D laboratories, academic research institutions, and biotechnology companies focused on neuroscience, gastroenterology, and metabolic disorder research.

Application

• Biochemical Research: As a standard or reference compound in studies investigating the structure-activity relationship (SAR) of cholecystokinin peptides.
• Neuroscience Studies: For probing the role of CCK in the central nervous system, including its effects on anxiety, pain perception, and dopamine release.
• Receptor Binding Assays: Used in competitive binding experiments to characterize CCK receptor subtypes (CCKA and CCKB/gastrin receptors) and screen for potential agonists or antagonists.
• Pharmaceutical Development: Serves as a key intermediate or pharmacophore model in the design and synthesis of novel therapeutic agents targeting CCK pathways.
• Diagnostic Tool Development: Potential use in the development of assays or imaging agents to study CCK-related physiological processes.

Basic Information

Product Name	Cholecystokinin (27-32) Amide, Benzoyloxycarbonyl-
CAS No.	92773-91-6
Molecular Formula	C46H61N9O9
Molecular Weight	884.04 g/mol
Synonyms	Boc-CCK-6; Z-CCK-6; Cholecystokinin Fragment 27-32 Amide, Benzyloxycarbonyl-; CCK (27-32), Amide, N-Benzyloxycarbonyl-; Benzyloxycarbonyl-Asp-Tyr(SO3H)-Met-Gly-Trp-Met-Asp-Phe-NH2 (CCK-8 related fragment); Z-Asp-Tyr(SO3H)-Met-Gly-Trp-Met-NH2; CCK-6 (sulfated), Z-protected; CCK Hexapeptide Amide, Z-derivative
EINECS	Contact for details

Quality Control

Our Cholecystokinin (27-32) Amide, Benzoyloxycarbonyl- is manufactured under strict quality systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, mass spectrometry (MS) for identity confirmation, and amino acid analysis (AAA). We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with research-grade specifications. Our commitment to consistent quality and batch-to-batch reproducibility supports reliable experimental outcomes.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to minimize moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC-MS)	Conforms to structure
Purity (HPLC)	≥ 95%
Single Impurity (HPLC)	≤ 2.0%
Amino Acid Composition	Conforms to theoretical values
Water Content (KF)	≤ 5.0%
Peptide Content	≥ 80%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.