Description

Tyrosylarginine Methyl Ester is a high-purity, synthetic dipeptide derivative combining the aromatic amino acid tyrosine with the basic amino acid arginine in a methyl ester form. This compound is of significant interest in biochemical research and pharmaceutical development due to its role as a potential enzyme substrate or intermediate in peptide synthesis. It is primarily utilized by research institutions, pharmaceutical R&D departments, and fine chemical manufacturers focused on proteomics, enzyme kinetics, and novel therapeutic agent discovery.

Application

• Biochemical Research: Used as a specific substrate or inhibitor in studies of proteolytic enzymes like trypsin, thrombin, and other serine proteases.
• Pharmaceutical Intermediates: Serves as a key building block in the solid-phase or solution-phase synthesis of more complex bioactive peptides and peptidomimetics.
• Proteomics & Enzymology: Employed in assay development to study enzyme specificity, kinetics, and mechanism of action in metabolic pathways.
• Diagnostic Reagent Development: Acts as a component in the formulation of chromogenic or fluorogenic substrates for clinical diagnostic kits.
• Academic Research: Utilized in university and institutional labs for fundamental studies in peptide chemistry, medicinal chemistry, and molecular biology.
• Fine Chemical Synthesis: An intermediate for the preparation of specialized compounds used in life science research and development.

Basic Information

Product Name	Tyrosylarginine Methyl Ester
CAS No.	92758-99-1
Molecular Formula	C17H26N6O4
Molecular Weight	378.43 g/mol
Synonyms	L-Tyrosyl-L-arginine methyl ester; Tyr-Arg-OMe; H-Tyr-Arg-OMe; Nα-[(9H-Fluoren-9-ylmethoxy)carbonyl]-Nω-[(2,2,4,6,7-pentamethyldihydrobenzofuran-5-yl)sulfonyl]-L-arginine; Fmoc-Arg(Pbf)-OH (related protected form); Methyl L-tyrosyl-L-argininate; TAME (context-specific); Peptide derivative CAS 92758-99-1
EINECS	Contact for details

Quality Control

Our Tyrosylarginine Methyl Ester is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and specific optical rotation measurement. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your research or production specifications. Custom purity grades, including research and pharmaceutical intermediates, are available.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C for long-term stability. This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to prevent absorption of atmospheric moisture. For bulk quantities, store under an inert atmosphere in a dedicated, temperature-controlled environment.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (MS)	Conforms
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Specific Optical Rotation	Contact for details
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.