Description

4,6-Dichloro-2-(4-Methylphenyl)-5-Pyrimidinamine is a halogenated pyrimidine derivative that serves as a critical synthetic intermediate in advanced organic chemistry. Its value lies in its functionalized structure, which provides reactive sites for constructing complex heterocyclic systems. This compound is primarily needed by research institutions and pharmaceutical manufacturers for the development of active pharmaceutical ingredients (APIs) and agrochemicals.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, particularly in antiviral and anticancer research.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides due to its pyrimidine core.
• Material Science Research: Serves as a precursor for creating specialized organic ligands and functional polymers.
• Chemical Research & Development: A versatile reagent for exploring new heterocyclic coupling reactions and molecular scaffolds.
• Custom Synthesis: Employed by contract research organizations (CROs) and CDMOs for client-specific molecule development.

Basic Information

Product Name	4,6-Dichloro-2-(4-Methylphenyl)-5-Pyrimidinamine
CAS No.	92616-67-6
Molecular Formula	C11H9Cl2N3
Molecular Weight	254.11 g/mol
Synonyms	5-Amino-4,6-dichloro-2-p-tolylpyrimidine; 2-(4-Methylphenyl)-4,6-dichloro-5-pyrimidinamine; 4,6-Dichloro-2-(p-tolyl)-5-pyrimidinamine; 4,6-Dichloro-2-(4-methylphenyl)pyrimidin-5-amine; 4,6-Dichloro-2-(p-methylphenyl)-5-aminopyrimidine; 4,6-Dichloro-2-(4-tolyl)-5-aminopyrimidine; 5-Pyrimidinamine, 4,6-dichloro-2-(4-methylphenyl)-
EINECS	Contact for details

Quality Control

Our 4,6-Dichloro-2-(4-Methylphenyl)-5-Pyrimidinamine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing purity (typically ≥95% by HPLC), identity confirmation, and impurity profiles are available for every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%
Single Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.