Description

Ipsapirone CAS NO 92589-98-5 is a high-purity azapirone derivative and a selective 5-HT1A receptor agonist. This compound is of significant interest for its pharmacological profile, serving as a critical reference standard and active pharmaceutical ingredient (API) in research and development. It is primarily utilized by pharmaceutical companies, contract research organizations (CROs), and academic institutions engaged in neuroscience and psychopharmacology studies.

Application

• Pharmaceutical Reference Standard: Used for the calibration of analytical instruments, method validation, and quality control in API and finished product manufacturing.
• Neuroscience Research: A key tool compound for studying the function and modulation of the serotonin 5-HT1A receptor system in vitro and in vivo.
• Drug Discovery & Development: Serves as a lead compound or intermediate in the synthesis of novel anxiolytic and antidepressant therapeutic candidates.
• Preclinical Studies: Employed in animal models to investigate mechanisms of action, pharmacokinetics, and efficacy for anxiety and mood disorders.
• Biochemical Assays: Used in receptor binding studies and high-throughput screening (HTS) to identify and characterize new receptor ligands.

Basic Information

Product Name	Ipsapirone
CAS No.	92589-98-5
Molecular Formula	C₁₈H₂₅N₃O₂
Molecular Weight	315.41 g/mol
Synonyms	Ipsapirone; 2-(4-(4-(Pyrimidin-2-yl)piperazin-1-yl)butyl)-1,2-benzisothiazol-3(2H)-one 1,1-dioxide; Bay q 7821; TVX Q 7821; Ipsapirone Hydrochloride (salt form)
EINECS	Contact for details

Quality Control

Our Ipsapirone is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide Certificates of Analysis (COA) with detailed results from advanced techniques like HPLC, NMR, and mass spectrometry. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates and reference standards, ensuring reliability for your critical research and development projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.