Description

L-Isovaline, 3-Mercapto-3-Methyl- (9Ci) is a specialized non-proteinogenic amino acid derivative featuring a unique thiol group, making it a valuable chiral building block and intermediate in advanced organic synthesis. Its structure is critical for applications requiring precise stereochemistry and sulfur-based reactivity, offering researchers and manufacturers a high-purity tool for complex molecule construction. This compound is primarily utilized by pharmaceutical R&D teams, agrochemical innovators, and specialty chemical producers developing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon in the research and development of novel therapeutic agents, particularly for central nervous system (CNS) targets and enzyme inhibitors.
• Agrochemical Synthesis: Used in the creation of advanced, stereospecific pesticides and herbicides where the thiol functionality and specific chirality are essential for bioactivity.
• Peptidomimetics & Bioactive Peptide Research: Incorporated into peptide analogs to study structure-activity relationships (SAR) and to enhance metabolic stability or binding affinity.
• Ligand & Catalyst Development: Acts as a precursor for chiral ligands used in asymmetric catalysis, enabling more efficient and selective chemical transformations.
• Biochemical Research: Employed as a probe or substrate in enzymatic studies to investigate metabolic pathways involving sulfur-containing amino acids.
• Material Science: Potential use in the synthesis of functionalized polymers or surfaces where the thiol group allows for specific conjugation or modification.

Basic Information

Product Name	L-Isovaline, 3-Mercapto-3-Methyl- (9Ci)
CAS No.	92462-81-2
Molecular Formula	C6H11NO2S
Molecular Weight	161.22 g/mol
Synonyms	(2S)-2-Amino-3-mercapto-3-methylbutanoic acid; L-3-Mercapto-3-methylisovaline; (S)-2-Amino-3-mercapto-3-methylbutyric acid; 3-Mercapto-3-methyl-L-isovaline; 3-Methyl-3-mercaptoisovaline; 3-Methyl-3-thioisovaline; L-3-Methyl-3-mercaptoisovaline
EINECS	Contact for details

Quality Control

Our L-Isovaline, 3-Mercapto-3-Methyl- (9Ci) is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification and impurity profiling, to ensure it meets the high standards required for research and synthesis. Certificates of Analysis (COA) detailing specific results for identity, purity, and related substances are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C) under an inert atmosphere (e.g., nitrogen or argon) to prevent oxidation of the thiol group. Keep away from strong oxidizing agents and moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee (L-Isomer)
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.