Description

n-(6-Chloro-4-Phenylquinazolin-2-Yl)Guanidine is a high-purity, specialized quinazoline derivative with significant potential in advanced chemical synthesis. This compound serves as a critical building block and intermediate for the development of novel pharmaceutical agents and bioactive molecules. It is primarily sought by research institutions and chemical manufacturers engaged in medicinal chemistry, particularly for the synthesis of targeted kinase inhibitors and other therapeutic candidates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel quinazoline-based drug candidates targeting various disease pathways.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Kinase Inhibitor Development: Serves as a building block for creating potential inhibitors of tyrosine kinases and other enzyme targets relevant in oncology.
• Biochemical Research: Employed in the study of protein-ligand interactions and the development of high-throughput screening assays.
• Fine Chemical Synthesis: Utilized in multi-step organic syntheses to introduce the guanidine-functionalized quinazoline moiety into more complex molecular architectures.

Basic Information

Product Name	n-(6-Chloro-4-Phenylquinazolin-2-Yl)Guanidine
CAS No.	92434-13-4
Molecular Formula	C15H12ClN5
Molecular Weight	297.74 g/mol
Synonyms	2-Guanidino-6-chloro-4-phenylquinazoline; N-(6-Chloro-4-phenyl-2-quinazolinyl)guanidine; Guanidine, N-(6-chloro-4-phenyl-2-quinazolinyl)-; 6-Chloro-4-phenyl-2-guanidinoquinazoline; 92434-13-4; (6-Chloro-4-phenylquinazolin-2-yl)guanidine
EINECS	Contact for details

Quality Control

Our n-(6-Chloro-4-Phenylquinazolin-2-Yl)Guanidine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, IR, MS), to ensure compliance with research and development grade specifications. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.