Description

Poly(Lysly-Glutamine) is a synthetic polypeptide composed of alternating lysine and glutamine residues. This engineered biopolymer is valued for its unique structural and functional properties, bridging the gap between synthetic polymers and natural proteins. It is primarily utilized in advanced biomedical research, pharmaceutical development, and specialized material science applications where precise molecular architecture and biocompatibility are critical.

Application

• Biomedical Research: Serves as a model compound for studying protein folding, peptide interactions, and enzyme-substrate dynamics.
• Drug Delivery Systems: Investigated as a component in biodegradable carriers for controlled release of therapeutic agents.
• Tissue Engineering Scaffolds: Used in the development of synthetic extracellular matrices to support cell growth and tissue regeneration.
• Biomaterial Coatings: Applied to modify surface properties of implants to enhance biocompatibility and reduce immune response.
• Enzyme Mimics & Catalysis: Explored for creating synthetic enzymes or catalytic peptides due to its defined amino acid sequence.
• Cosmeceutical Formulations: Incorporated in high-performance skincare for its potential film-forming and moisturizing properties.

Basic Information

Product Name	Poly(Lysly-Glutamine)
CAS No.	92352-83-5
Molecular Formula	(C11H21N3O4)n
Molecular Weight	Variable (Polymer)
Synonyms	Poly(Lys-Gln); Poly(L-lysyl-L-glutamine); Poly(lysine-glutamine); Alternating Lys-Gln Polymer; Poly(Lys-Glu-NH2); Poly(K-Q); PLG; Synthetic Polypeptide (Lys, Gln)
EINECS	Contact for details

Quality Control

Our Poly(Lysly-Glutamine) is produced under controlled conditions to ensure batch-to-batch consistency. Quality is verified through a suite of analytical techniques including HPLC for purity, amino acid analysis for composition, and spectroscopy for structural confirmation. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing key parameters such as molecular weight distribution, endotoxin levels (where applicable), and residual solvent content.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term stability, consider storage under inert atmosphere or at -20°C.

Specification

Item	Specification
Appearance	White to off-white powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95%
Amino Acid Ratio (Lys:Gln)	~1:1
Average Molecular Weight	Specified per grade (e.g., 5kDa, 10kDa, 20kDa)
Moisture Content (KF)	≤ 5.0%
Endotoxin (LAL)	< 10 EU/mg (for research grades)
Solubility	Soluble in water, aqueous buffers

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.