Description

2-Pyrimidinamine, 4-Fluoro-6-(Fluoromethyl)- (9Ci) is a specialized fluorinated pyrimidine derivative, a high-value building block in advanced organic synthesis. Its molecular structure, featuring both a fluoro and a fluoromethyl substituent, makes it a critical intermediate for introducing fluorine atoms into target molecules, a key strategy in modern pharmaceutical and agrochemical design. This compound is essential for researchers and process chemists in the life sciences sector developing novel active ingredients with enhanced properties.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of novel active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other targeted therapies.
• Agrochemical Synthesis: Used in the creation of advanced herbicides, fungicides, and pesticides where the introduction of fluorine improves metabolic stability and bioactivity.
• Material Science Research: Serves as a precursor for fluorinated heterocyclic compounds used in the development of specialty polymers and electronic materials.
• Chemical Biology & Probe Development: Utilized in the synthesis of molecular probes and labeled compounds for studying biological mechanisms and diagnostics.
• Custom Synthesis & Contract Manufacturing: A vital starting material for fine chemical manufacturers offering bespoke synthesis services to the pharmaceutical and biotechnology industries.

Basic Information

Product Name	2-Pyrimidinamine, 4-Fluoro-6-(Fluoromethyl)- (9Ci)
CAS No.	92311-40-5
Molecular Formula	C5H5F2N3
Molecular Weight	145.11 g/mol
Synonyms	4-Fluoro-6-(fluoromethyl)pyrimidin-2-amine; 2-Amino-4-fluoro-6-(fluoromethyl)pyrimidine; 4-Fluoro-6-fluoromethyl-2-pyrimidinamine; 92311-40-5; 4-Fluoro-6-(fluoromethyl)-2-pyrimidinamine
EINECS	Contact for details

Quality Control

Every batch of our 4-Fluoro-6-(fluoromethyl)pyrimidin-2-amine is produced and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for research and scale-up activities. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles by HPLC, NMR, and MS is supplied with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). Keep away from incompatible materials such as strong acids, strong bases, and strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC/MS)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.