Description

Somatotropin Releasing Hormone, N(Alpha) Biotinyl(1-44)Amide is a biotinylated analog of the growth hormone-releasing hormone (GHRH) peptide. This modification is crucial for enhancing detection and purification processes in advanced biochemical research and diagnostic applications. This high-purity peptide is primarily utilized by research institutions, pharmaceutical developers, and diagnostic manufacturers engaged in endocrinology, metabolic studies, and assay development.

Application

• Biochemical Research: Used as a specific ligand or tracer in receptor binding studies and signal transduction research related to growth hormone secretion.
• Diagnostic Assay Development: Serves as a critical component in the development of immunoassays (e.g., ELISA) for detecting GHRH or related antibodies.
• Affinity Purification: The biotin tag enables efficient capture via streptavidin/avidin matrices for purifying specific antibodies or receptor proteins.
• Pharmaceutical R&D: Employed in preclinical studies to investigate the modulation of the somatotropic axis and evaluate potential therapeutic candidates.
• Cell Culture & In Vitro Studies: Applied in controlled laboratory settings to study the direct effects of GHRH analogs on pituitary cell function.

Basic Information

Product Name	Somatotropin Releasing Hormone, N(Alpha) Biotinyl(1-44)Amide
CAS No.	92170-23-5
Molecular Formula	C235H366N72O68S2
Molecular Weight	Approx. 5180.0 g/mol
Synonyms	Biotinyl-GHRH(1-44)-NH2; Biotinylated Growth Hormone-Releasing Hormone (1-44) Amide; N-α-Biotinyl-GHRH(1-44)amide; GHRH (1-44), Biotinylated; Somatoliberin (1-44) amide, N(alpha)-Biotinyl-; Biotin-GHRH; Biotin-Somatoliberin(1-44)amide; Biotinylated Somatotropin Releasing Factor
EINECS	Contact for details

Quality Control

Our Somatotropin Releasing Hormone, N(Alpha) Biotinyl(1-44)Amide is manufactured under stringent conditions to ensure batch-to-batch consistency and high biological activity. Quality is verified through a comprehensive suite of analytical techniques including HPLC, MS, and amino acid analysis. A Certificate of Analysis (COA) detailing purity, peptide content, and biotin incorporation ratio is provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dedicated freezer. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to prevent condensation and moisture uptake. For long-term storage, consider under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Peptide Content	≥ 80% (by weight)
Amino Acid Analysis	Within ± 10% of theoretical
Water Content (KF)	≤ 5.0%
Solubility	Soluble in water or dilute acetic acid

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.