Description

Insulin B (20-30) CAS NO 91921-56-1 is a defined chain fragment of the insulin B-chain, specifically encompassing amino acid residues 20 through 30. This high-purity peptide is a critical reference standard and building block for advanced biochemical research and pharmaceutical development. It is essential for scientists and manufacturers engaged in metabolic disorder studies, peptide synthesis, and the quality control of insulin-based therapeutics.

Application

• Pharmaceutical Reference Standard: Used for the identification, purity assessment, and quantification of insulin and its analogs in quality control laboratories.
• Biochemical Research: Serves as a key reagent in structure-activity relationship (SAR) studies to understand insulin receptor binding and function.
• Peptide Synthesis: Acts as a protected intermediate or a model fragment in the solid-phase or solution-phase synthesis of full-length insulin or novel insulin mimetics.
• Diagnostic Development: Utilized in the development and calibration of immunoassays (e.g., ELISA) for detecting insulin and related peptides.
• Metabolic Studies: Employed in in vitro and ex vivo research to investigate insulin signaling pathways, degradation, and diabetes mechanisms.

Basic Information

Product Name	Insulin B (20-30)
CAS No.	91921-56-1
Molecular Formula	C58H89N17O19S2
Molecular Weight	1384.56 g/mol
Synonyms	Insulin B-Chain Fragment 20-30; B(20-30)-Insulin; H-Gly-Glu-Arg-Gly-Phe-Phe-Tyr-Thr-Pro-Lys-Thr-OH; Insulin B Chain (20-30) Peptide; Insulin B (20-30) peptide; [Gly20, Glu21, Arg22, Gly23, Phe24, Phe25, Tyr26, Thr27, Pro28, Lys29, Thr30]-Insulin B-Chain
EINECS	Contact for details

Quality Control

Our Insulin B (20-30) is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including reversed-phase HPLC for purity, mass spectrometry for identity confirmation, and amino acid analysis. A Certificate of Analysis (COA) detailing all specifications and test results is provided to ensure traceability and compliance with your research or cGMP guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to prevent condensation and moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC & MS)	Conforms to reference standard
Purity (HPLC)	≥ 95.0%
Single Impurity (HPLC)	≤ 2.0%
Amino Acid Composition	Within ±10% of theoretical
Water Content (KF)	≤ 8.0%
Peptide Content	≥ 70.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.