Description

Anp 1-28, Human is a synthetic peptide fragment corresponding to the N-terminal region of human Atrial Natriuretic Peptide (ANP). This high-purity reference standard is critical for research and development in cardiovascular and renal physiology. It is primarily utilized by pharmaceutical researchers, diagnostic kit manufacturers, and academic institutions for bioactivity studies, assay calibration, and as a key intermediate in therapeutic development.

Application

• Biomedical Research: Used as a reference standard in studies investigating the natriuretic peptide system, its receptors, and signaling pathways.
• Diagnostic Development: Serves as a critical calibrant and control material in the development and validation of immunoassays (e.g., ELISA, RIA) for ANP-related biomarkers.
• Pharmaceutical R&D: Employed as a key intermediate or reference compound in the discovery and development of novel cardiovascular therapeutics targeting heart failure and hypertension.
• Quality Control: Acts as a system suitability standard in analytical laboratories to validate methods for peptide identification and quantification (e.g., HPLC, LC-MS).
• Academic Studies: Facilitates fundamental research in physiology and endocrinology related to blood pressure regulation, fluid balance, and cardiac function.

Basic Information

Product Name	Anp 1-28, Human
CAS No.	91917-63-4
Molecular Formula	C128H205N43O41S2
Molecular Weight	3080.4 g/mol
Synonyms	Atrial Natriuretic Peptide (1-28), human; ANP (1-28); Atriopeptin (1-28); Cardionatrin (1-28); Auriculin A (1-28); hANP; α-ANP; Atrial Natriuretic Factor (1-28)
EINECS	Contact for details

Quality Control

Our Anp 1-28, Human is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including identity confirmation by mass spectrometry (MS) and purity assessment by high-performance liquid chromatography (HPLC). We provide full traceability and Certificates of Analysis (COA) are available for all shipments, detailing purity, peptide content, and related substance profiles to ensure compliance with your research specifications.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a freezer. The product is hygroscopic (moisture-sensitive). Allow the vial to reach room temperature in a desiccator before opening to prevent condensation and moisture uptake. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (MS)	Consistent with theoretical molecular weight
Purity (HPLC)	≥ 95%
Peptide Content	≥ 80% (by weight)
Water Content (KF)	≤ 5.0%
Acetate Content (HPLC)	≤ 10.0%
Single Impurity (HPLC)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.