Description

Pyroglutamyl-Glutamyl-Asparaginyl-Glycine is a synthetic tetrapeptide with the sequence pGlu-Glu-Asn-Gly. This compound is a valuable biochemical tool and a key intermediate in peptide synthesis and research. It is primarily utilized in the pharmaceutical and biotechnology sectors for the development of novel therapeutic agents, diagnostic tools, and as a reference standard. The product is supplied under stringent quality control to ensure consistency and reliability for critical research and manufacturing applications.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of longer, more complex peptide-based drugs and active pharmaceutical ingredients (APIs).
• Biochemical Research: Used as a reference standard, substrate, or inhibitor in enzymatic studies and metabolic pathway investigations.
• Cosmeceutical Development: Incorporated into research for bioactive peptides aimed at skincare formulations for anti-aging or skin barrier repair.
• Diagnostic Reagent Component: Employed in the development of immunoassays and other diagnostic kits where specific peptide sequences are required.
• Cell Culture & Media Supplement: Investigated for use in specialized cell culture media to study cell signaling and growth factors.
• Neuroscience Research: Applied in studies related to neuropeptides and their role in neurological functions and disorders.

Basic Information

Product Name	Pyroglutamyl-Glutamyl-Asparaginyl-Glycine
CAS No.	91856-42-7
Molecular Formula	C17H25N5O10
Molecular Weight	459.41 g/mol
Synonyms	pGlu-Glu-Asn-Gly; Pyr-Glu-Glu-Asn-Gly-OH; L-Pyroglutamyl-L-glutamyl-L-asparaginyl-glycine; 5-Oxo-L-prolyl-L-α-glutamyl-L-asparaginylglycine; Tetrapeptide pGlu-Glu-Asn-Gly; Glp-Glu-Asn-Gly; pGlu-Glu-Asn-Gly-OH; N-(N-(N-(N-L-Pyroglutamyl-L-α-glutamyl)-L-asparaginyl)glycine
EINECS	Contact for details

Quality Control

Our Pyroglutamyl-Glutamyl-Asparaginyl-Glycine is manufactured under a quality management system and undergoes rigorous analytical testing to ensure it meets high-purity standards suitable for research and development. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We support compliance with relevant guidelines for pharmaceutical intermediates and research chemicals.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms to structure
Identification (IR)	Conforms to reference
Assay (HPLC)	≥ 95.0%
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.