Description

5-Iodo-4-Methylpyrimidine CAS NO 91749-26-7 is a halogenated pyrimidine derivative, a versatile and valuable building block in advanced organic synthesis. Its core value lies in its role as a key intermediate for constructing complex molecules, particularly in the development of active pharmaceutical ingredients (APIs) and functional materials. This compound is essential for research and production teams in the pharmaceutical, agrochemical, and specialty chemical industries seeking to introduce iodine and pyrimidine motifs into their target structures.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of novel drug candidates, especially nucleoside analogs and kinase inhibitors.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and plant growth regulators.
• Material Science Research: Serves as a building block for creating organic electronic materials, ligands for metal complexes, and liquid crystals.
• Chemical Biology & Proteomics: Employed in the design of molecular probes, tags, and inhibitors for studying biological systems.
• Cross-Coupling Reactions: Acts as a substrate in palladium-catalyzed reactions (e.g., Suzuki, Sonogashira) for carbon-carbon bond formation.
• Academic & Contract Research: A standard reagent for methodological development and exploratory chemistry in university and CRO laboratories.

Basic Information

Product Name	5-Iodo-4-Methylpyrimidine
CAS No.	91749-26-7
Molecular Formula	C5H5IN2
Molecular Weight	220.01 g/mol
Synonyms	4-Methyl-5-iodopyrimidine; 5-Iodo-4-methylpyrimidine; 4-Methyl-5-iodo-pyrimidine; Pyrimidine, 5-iodo-4-methyl-; 91749-26-7; 5-Iodo-4-methyl-pyrimidine; 4-Methyl-5-iodo-1,3-diazine
EINECS	Contact for details

Quality Control

Our 5-Iodo-4-Methylpyrimidine is produced under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and consistent performance. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment and are available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, handling and storage should minimize exposure to direct light.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.