Description

Norleucine, 6-Mercato- is a specialized amino acid derivative featuring a thiol (-SH) functional group on its side chain, making it a valuable building block for peptide synthesis and biochemical research. This compound is particularly significant for introducing specific chemical handles or modifying the redox properties of peptides and proteins. It is primarily utilized by researchers and manufacturers in the pharmaceutical, biotechnology, and life science sectors for applications ranging from drug discovery to the development of novel biomaterials.

Application

• Peptide Synthesis: Used as a non-natural amino acid building block in solid-phase and solution-phase peptide synthesis to incorporate thiol functionality.
• Bioconjugation & Protein Labeling: The reactive thiol group serves as a site-specific anchor for attaching fluorescent dyes, biotin, polyethylene glycol (PEG), or other probes.
• Chemical Biology Research: Employed in studying protein structure-function relationships, enzyme mechanisms, and redox biology due to its modifiable side chain.
• Pharmaceutical Intermediate: Acts as a key chiral intermediate in the synthesis of more complex active pharmaceutical ingredients (APIs) and drug candidates.
• Material Science: Can be incorporated into polymers or hydrogels to create smart materials with responsive or adhesive properties.

Basic Information

Product Name	Norleucine, 6-Mercapto-
CAS No.	91724-74-2
Molecular Formula	C6H13NO2S
Molecular Weight	163.24 g/mol
Synonyms	6-Mercaptonorleucine; DL-6-Mercaptonorleucine; 2-Amino-6-mercaptohexanoic acid; Homo cysteine; (RS)-2-Amino-6-mercaptohexanoic acid; 6-Thianorleucine; Aminohexanoic acid, 6-mercapto-
EINECS	Contact for details

Quality Control

Our Norleucine, 6-Mercapto- is produced under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC for purity, chiral analysis, and identity confirmation, to ensure it meets the high standards required for research and synthesis. Certificates of Analysis (COA) detailing all specifications are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its sensitivity to oxidation, it is recommended to handle under an inert atmosphere for long-term storage or after opening. Keep the container tightly sealed to minimize exposure to air and moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Optical Purity (Chiral HPLC)	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.