Description

6'-n-Formimidoylamikacin is a chemically modified derivative of the aminoglycoside antibiotic amikacin. This compound is of significant interest in pharmaceutical research and development, particularly for the synthesis of novel antibiotic agents and the study of structure-activity relationships. It serves as a crucial advanced pharmaceutical intermediate for researchers and manufacturers in the life sciences sector who require high-purity building blocks for antibiotic innovation.

Application

• Pharmaceutical Intermediate: Primary use in the research and synthesis of next-generation aminoglycoside antibiotics.
• Antibacterial Research: A key reference standard and building block in studies aimed at overcoming bacterial resistance mechanisms.
• Medicinal Chemistry: Used for the structural modification of amikacin to develop analogs with improved efficacy or reduced toxicity profiles.
• Biochemical Studies: Employed in research investigating the interaction between aminoglycosides and bacterial ribosomes or modifying enzymes.
• GMP Manufacturing: Serves as a starting material or intermediate in the controlled production of active pharmaceutical ingredients (APIs) under Good Manufacturing Practice guidelines.

Basic Information

Product Name	6'-n-Formimidoylamikacin
CAS No.	91704-91-5
Molecular Formula	C22H45N5O13
Molecular Weight	587.62 g/mol
Synonyms	1-N-[(S)-4-Amino-2-hydroxybutyryl]-6'-N-formimidoylkanamycin A; 6'-N-Formimidoylamikacin; Formimidoylamikacin; 6'-N-Formimidoyl-1-N-[(S)-4-amino-2-hydroxybutyryl]kanamycin A; Amikacin 6'-N-formimidoyl derivative; Antibiotic BB-K 311; BBK 311
EINECS	Contact for details

Quality Control

Every batch of 6'-n-Formimidoylamikacin is produced and tested to meet stringent quality standards suitable for research and pharmaceutical applications. Our quality assurance protocol includes identity confirmation, purity assay, and impurity profiling to ensure batch-to-batch consistency and reliability. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with each shipment to support your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 1.0%
Related Substances (HPLC)	Total impurities ≤ 3.0% Any single impurity ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.