Description

6'-n-Formimidoyldibekacin is a chemically modified derivative of the aminoglycoside antibiotic dibekacin, characterized by the introduction of a formimidoyl group. This structural modification is of significant interest in pharmaceutical research for its potential to alter biological activity, pharmacokinetic properties, or reduce toxicity profiles. It serves as a critical advanced pharmaceutical intermediate or reference standard for researchers and manufacturers in the life sciences sector. Target users include organizations engaged in the development of novel antibiotics, analytical method validation, and high-purity chemical synthesis.

Application

• Pharmaceutical Intermediate: Key starting material or advanced intermediate in the research and synthesis of novel aminoglycoside antibiotic derivatives.
• Reference Standard: High-purity compound used for analytical method development, validation, and quality control (QC) in pharmaceutical laboratories.
• Biochemical Research: Tool compound for studying structure-activity relationships (SAR), microbial resistance mechanisms, and enzymatic modification of aminoglycosides.
• API Development: Investigational material in pre-clinical and early-stage development of new antibacterial agents.

Basic Information

Product Name	6'-n-Formimidoyldibekacin
CAS No.	91704-85-7
Molecular Formula	C20H39N5O9
Molecular Weight	493.56 g/mol
Synonyms	6'-N-Formimidoyldibekacin; 1-N-[(S)-4-Amino-2-hydroxybutyryl]-6'-N-formimidoyldibekacin; Dibekacin 6'-N-formimidoyl derivative; Formimidoyldibekacin; Antibiotic XK-62-2 derivative; (2S)-4-Amino-N-[(1R,2S,3S,4R,5S)-5-amino-4-[(2S,3R,4S,5S,6R)-4-amino-3,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-2-[(2R,3R,4S,5S,6R)-4-amino-3,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-3-hydroxycyclohexyl]-2-hydroxybutanamide
EINECS	Contact for details

Quality Control

Our 6'-n-Formimidoyldibekacin is produced and handled under a strict quality management system. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) that detail specifications and results from advanced techniques such as HPLC, NMR, and mass spectrometry. Our quality commitment supports applications requiring high-purity reference standards and pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.