Description

(3,4-Dehydro-Pro3)-Tuftsin CAS NO 91502-65-7 is a synthetic, biologically active peptide analog of the natural immunomodulatory tetrapeptide tuftsin. This modified compound is engineered for enhanced stability and specific receptor interaction, making it a critical research tool for studying immune system modulation and peptide-based drug discovery. It is primarily utilized by pharmaceutical R&D teams, academic researchers, and biotechnology companies focused on immunology, oncology, and novel therapeutic development.

Application

• Immunological Research: Used as a reference standard and active agent in studies of macrophage activation, phagocytosis, and cytokine regulation.
• Drug Discovery & Development: Serves as a lead compound or pharmacophore for designing new immunomodulatory and anti-cancer peptide therapeutics.
• Biochemical Assays: Employed in in vitro and cell-based assays to investigate specific receptor-ligand interactions and signal transduction pathways.
• Peptide Chemistry Studies: Acts as a model compound for studying structure-activity relationships (SAR) of modified peptides, particularly those with dehydroamino acids.
• Academic & Pharmaceutical R&D: Essential for basic research and preclinical studies in university and industrial laboratories exploring innate immunity.

Basic Information

Product Name	(3,4-Dehydro-Pro3)-Tuftsin
CAS No.	91502-65-7
Molecular Formula	C23H34N6O7
Molecular Weight	506.55 g/mol
Synonyms	Dehydroproline3-Tuftsin; [δ3-Pro3]-Tuftsin; Thr-Lys-δPro-Arg; L-Threonyl-L-lysyl-(3,4-dehydro-L-prolyl)-L-arginine; Tuftsin (3,4-dehydro-Pro3); Immunomodulatory Peptide Analog; H-Thr-Lys-δPro-Arg-OH
EINECS	Contact for details

Quality Control

Every batch of (3,4-Dehydro-Pro3)-Tuftsin is manufactured under strict quality management systems and undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide full traceability and Certificates of Analysis (COA) detailing purity by HPLC, amino acid analysis, and mass spectrometry. Our quality commitment aligns with standards expected for pharmaceutical research materials.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95.0%
Amino Acid Composition	Conforms to theoretical values
Water Content (KF)	≤ 5.0%
Peptide Content	≥ 80.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.