Description

Minigastrin, Des-Trp(1)-Nle(12)- is a synthetic peptide analog of the human gastrin hormone, specifically designed for research and diagnostic applications. This compound is valued for its high purity and stability, making it a critical reagent in biochemical and pharmaceutical research. It is primarily utilized by research institutions, diagnostic kit manufacturers, and pharmaceutical companies engaged in gastrointestinal hormone studies and assay development.

Application

• Biochemical Research: Used as a specific ligand in receptor binding studies and signal transduction research related to the gastrin/CCK-B receptor.
• Diagnostic Assays: Serves as a key component in the development and calibration of immunoassays (e.g., ELISA, RIA) for measuring gastrin levels.
• Pharmaceutical Development: Employed as a reference standard in the discovery and testing of therapeutic agents targeting gastrointestinal disorders.
• Cell Culture & Physiology Studies: Applied in vitro to stimulate gastric acid secretion and study the physiological effects of gastrin on target cells.
• Quality Control: Used as a certified reference material (CRM) to ensure the accuracy and consistency of diagnostic tests in clinical laboratories.

Basic Information

Product Name	Minigastrin, Des-Trp(1)-Nle(12)-
CAS No.	91482-43-8
Molecular Formula	C58H83N13O16S
Molecular Weight	1234.4 g/mol
Synonyms	Des-Trp(1)-Nle(12)-Minigastrin; [Nle12]-Minigastrin (des-Trp1); Minigastrin I (2-17), 12-Norleucine; pGlu-Gly-Pro-Trp-Leu-(Glu)5-Ala-Tyr-Gly-Trp-Met-Asp-Phe-NH2 (with Trp1 deletion and Nle12 substitution); Gastrin I (2-17) fragment, 12-Norleucine analog; CCK-8/Gastrin related peptide analog
EINECS	Contact for details

Quality Control

Our Minigastrin, Des-Trp(1)-Nle(12)- is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing including HPLC for purity, mass spectrometry (MS) for identity confirmation, and amino acid analysis (AAA). Certificates of Analysis (COA) detailing purity, peptide content, and solvent residues are available upon request to support your regulatory and research documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). For long-term storage, consider desiccation. Allow the vial to reach room temperature before opening to minimize moisture absorption.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC & MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Peptide Content	≥ 80% (by AAA)
Single Impurity (HPLC)	≤ 1.0%
Water Content (KF)	≤ 5.0%
Acetate Content (HPLC)	≤ 10.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.