Description

H-His-Leu-Leu-Val-Phe-Ome is a synthetic pentapeptide derivative featuring a C-terminal methyl ester. This compound is a valuable research-grade biochemical tool, particularly for studying protease specificity and enzyme kinetics. It is primarily utilized by pharmaceutical R&D departments, academic research laboratories, and biotechnology companies engaged in peptide chemistry and drug discovery. The product is supplied as a high-purity material suitable for analytical and investigative applications.

Application

• Biochemical Research: Used as a specific substrate or inhibitor in enzymatic studies, particularly for investigating serine or cysteine proteases.
• Pharmaceutical Development: Serves as a key intermediate or reference standard in the synthesis and screening of novel peptide-based therapeutics.
• Proteomics & Enzymology: Employed in assays to determine enzyme activity, specificity constants (kcat/Km), and inhibition profiles.
• Academic Research: A critical reagent for university labs focusing on peptide metabolism, protein degradation pathways, and signal transduction mechanisms.
• Quality Control: Can be used as an analytical reference standard for method development and validation in QC laboratories.

Basic Information

Product Name	H-His-Leu-Leu-Val-Phe-Ome
CAS No.	91425-30-8
Molecular Formula	C36H55N7O6
Molecular Weight	681.87 g/mol
Synonyms	Histidyl-Leucyl-Leucyl-Valyl-Phenylalanine Methyl Ester; H-His-Leu-Leu-Val-Phe-OMe; HL-LV-F-OMe; Pentapeptide H-His-Leu-Leu-Val-Phe-Ome; 91425-30-8; L-Histidyl-L-leucyl-L-leucyl-L-valyl-L-phenylalanine methyl ester; Methyl L-histidyl-L-leucyl-L-leucyl-L-valyl-L-phenylalaninate
EINECS	Contact for details

Quality Control

Our H-His-Leu-Leu-Val-Phe-Ome is manufactured under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity, MS for identity confirmation, and chiral analysis to ensure stereochemical integrity. We provide full traceability and a Certificate of Analysis (COA) with every shipment, detailing all critical quality attributes to support your research and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to minimize moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC-MS)	Conforms
Purity (HPLC)	≥ 95.0%
Single Impurity (HPLC)	≤ 1.0%
Water Content (KF)	≤ 5.0%
Peptide Content	≥ 80.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.