Description

Dl-Erythro-4-Fluoroglutamic Acid CAS NO 91383-48-1 is a fluorinated derivative of the amino acid glutamic acid, serving as a valuable non-natural amino acid building block. This compound is significant for its role in modulating biological activity and altering metabolic pathways in research applications. It is primarily needed by pharmaceutical R&D teams and academic researchers focused on medicinal chemistry, enzyme inhibition studies, and the development of novel bioactive molecules.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new active pharmaceutical ingredients (APIs), particularly for neurological and metabolic targets.
• Medicinal Chemistry Research: Used as a probe or building block to study structure-activity relationships (SAR), enzyme inhibition, and receptor binding due to its fluorinated glutamic acid backbone.
• Biochemical Tool Compound: Employed in metabolic pathway studies to investigate the role of glutamate analogs in cellular processes.
• Peptide Synthesis: Incorporated into custom peptides to enhance stability, modulate bioavailability, or introduce specific fluorinated motifs for imaging or therapeutic purposes.
• Academic & Institutional Research: Serves as a standard or reagent in university and government labs for fundamental chemical and biological research.

Basic Information

Product Name	Dl-Erythro-4-Fluoroglutamic Acid
CAS No.	91383-48-1
Molecular Formula	C5H8FNO4
Molecular Weight	165.12 g/mol
Synonyms	4-Fluoroglutamic Acid (DL-erythro); DL-erythro-4-Fluoroglutamic Acid; (2R,4S)- and (2S,4R)-2-Amino-4-fluoropentanedioic Acid; (±)-erythro-4-Fluoroglutamic Acid; 4-Fluoro-DL-glutamic Acid (erythro); 2-Amino-4-fluoropentanedioic Acid (racemic erythro); NSC 339313; Fluoroglutamic Acid
EINECS	Contact for details

Quality Control

Our Dl-Erythro-4-Fluoroglutamic Acid is produced under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets high-purity research-grade standards. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent product degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Assay	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.