Description

Msh, 12-Bct-1-N(Alpha)-Dodecanoyl-Ser-4-Nle-7-Phe-α- CAS NO 91311-00-1 is a synthetic peptide derivative, specifically a modified analog of α-Melanocyte Stimulating Hormone (α-MSH). This compound is of significant interest in biochemical and pharmacological research due to its role in studying melanocortin receptor interactions and signaling pathways. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of therapeutics for metabolic disorders, inflammation, and skin pigmentation. The high-purity grade ensures reliable and reproducible results in sensitive assay systems.

Application

• Biomedical Research: As a key tool compound for studying the structure-activity relationships (SAR) of melanocortin peptides and their receptors (MC1R-MC5R).
• Drug Discovery: Serving as a reference standard or a lead compound in the development of novel therapeutics targeting obesity, metabolic syndrome, and inflammatory conditions.
• In Vitro Assays: Used in cell-based assays and receptor binding studies to evaluate agonist/antagonist activity and signal transduction mechanisms.
• Academic Studies: Fundamental research in endocrinology, neuroscience, and dermatology to understand the physiological roles of α-MSH analogs.
• Peptide Chemistry: As a model substrate for studying peptide stability, modification techniques, and analytical method development.

Basic Information

Product Name	Msh, 12-Bct-1-N(Alpha)-Dodecanoyl-Ser-4-Nle-7-Phe-α- CAS NO 91311-00-1
CAS No.	91311-00-1
Molecular Formula	C78H122N18O19S
Molecular Weight	1599.0 g/mol
Synonyms	12-Benzothiazole-α-MSH; [Nle4, D-Phe7]-α-MSH; Ac-[Nle4, Asp5, D-Phe7, Lys11]-α-MSH-(4-11)-NH2; α-Melanotropin (4-11), Nle4, D-Phe7-; Melanocyte Stimulating Hormone α-Analog; Ac-Ser-Tyr-Ser-Nle-Glu-His-D-Phe-Arg-Trp-Gly-Lys-Pro-Val-NH2 derivative; MT-II related peptide; SHU-9119 analog
EINECS	Contact for details

Quality Control

Our peptide products are manufactured and analyzed under strict quality management systems. Each batch of Msh, 12-Bct-1-N(Alpha)-Dodecanoyl-Ser-4-Nle-7-Phe-α- CAS NO 91311-00-1 undergoes comprehensive testing, including HPLC for purity, mass spectrometry for identity confirmation, and amino acid analysis. Certificates of Analysis (COA) detailing all specifications are provided to ensure traceability and compliance with research-grade standards.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). For long-term storage, it is recommended to store the lyophilized powder under inert atmosphere or in a desiccator. Allow the vial to equilibrate to room temperature before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC & MS)	Conforms to reference standard
Purity (HPLC)	≥ 95.0%
Single Impurity (HPLC)	≤ 1.0%
Amino Acid Analysis	± 10% of theoretical
Water Content (KF)	≤ 5.0%
Peptide Content	≥ 80.0%
Solubility	Soluble in DMSO, acetic acid; slightly soluble in water

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.