Description

Pyrimido[2,1-F]Purine-2,4,8(1H,3H,9H)-Trione, 7-[2-(Dimethylamino)Ethyl]-6-Hydroxy-1,3-Dimethyl-9-(Phenylmethyl)- is a complex purine derivative of significant interest in advanced organic synthesis and pharmaceutical research. This compound serves as a critical synthetic intermediate for developing novel therapeutic agents, particularly those targeting neurological and metabolic pathways. It is primarily needed by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the synthesis of high-value, specialized molecules.

Application

This specialized chemical intermediate is utilized in several high-value research and development applications:

• Pharmaceutical Intermediate: Key building block in the synthesis of novel purine-based drug candidates, including potential kinase inhibitors and neuromodulators.
• Biochemical Research: Used as a precursor or reference standard in studies exploring enzyme-substrate interactions, particularly those involving purine metabolism.
• Medicinal Chemistry: Serves as a core scaffold for structure-activity relationship (SAR) studies aimed at optimizing pharmacological properties.
• Fine Chemical Synthesis: Employed in multi-step synthetic routes to produce complex, high-purity molecules for academic and industrial research.
• Reference Standard: Used for analytical method development and validation (e.g., HPLC, LC-MS) in quality control laboratories.

Basic Information

Item	Details
Product Name	Pyrimido[2,1-F]Purine-2,4,8(1H,3H,9H)-Trione, 7-[2-(Dimethylamino)Ethyl]-6-Hydroxy-1,3-Dimethyl-9-(Phenylmethyl)-
CAS No.	91285-23-3
Molecular Formula	C₂₁H₂₆N₆O₄
Molecular Weight	426.47 g/mol
Synonyms	7-[2-(Dimethylamino)ethyl]-6-hydroxy-1,3-dimethyl-9-(phenylmethyl)pyrimido[2,1-f]purine-2,4,8(1H,3H,9H)-trione; 9-Benzyl-7-[2-(dimethylamino)ethyl]-6-hydroxy-1,3-dimethylpyrimido[2,1-f]purine-2,4,8-trione; 1H,3H,9H-Pyrimido[2,1-f]purine-2,4,8-trione, 7-[2-(dimethylamino)ethyl]-6-hydroxy-1,3-dimethyl-9-(phenylmethyl)-; 91285-23-3; 9-Benzyl-7-(2-dimethylaminoethyl)-6-hydroxy-1,3-dimethylpyrimido[2,1-f]purine-2,4,8-trione
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality management systems. Every batch undergoes comprehensive analytical characterization to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing specifications such as assay (HPLC), related substances, and residual solvents are provided and available upon request. We support cGMP-compliant manufacturing for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This material is moisture-sensitive; keep the container tightly sealed in a dry environment. For long-term storage, consider inert atmosphere conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single unknown impurity	≤ 0.5%
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.