Description

4-(Pyrimidin-5-Yl)Morpholine is a high-purity heterocyclic building block of significant interest in advanced organic synthesis. This compound matters as a key intermediate for constructing complex molecular architectures, particularly in the development of active pharmaceutical ingredients (APIs) and specialty agrochemicals. It is primarily needed by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and material science sectors seeking to innovate new functional molecules.

Application

• Pharmaceutical Intermediate: A crucial synthon for the research and development of novel drug candidates, particularly kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the creation of advanced fungicides, herbicides, and insecticides that require specific heterocyclic motifs for bioactivity.
• Ligand and Catalyst Development: Serves as a precursor for designing novel ligands in coordination chemistry and catalysis.
• Material Science Research: Employed in the synthesis of organic semiconductors, conductive polymers, and other functional organic materials.
• Chemical Biology Probes: Useful for synthesizing molecular probes to study biological pathways and protein functions.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects.

Basic Information

Product Name	4-(Pyrimidin-5-Yl)Morpholine
CAS No.	91233-71-5
Molecular Formula	C8H11N3O
Molecular Weight	165.19 g/mol
Synonyms	5-(4-Morpholinyl)pyrimidine; Morpholine, 4-(5-pyrimidinyl)-; 4-(Pyrimidin-5-yl)morpholine; 5-Morpholin-4-ylpyrimidine; Pyrimidine, 5-morpholino-; 91233-71-5; 4-(5-Pyrimidinyl)morpholine
EINECS	Contact for details

Quality Control

Our 4-(Pyrimidin-5-Yl)Morpholine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our commitment to quality supports compliance with cGMP and ICH guidelines for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.