Description

5-(Benzyloxy)-2,4-Dichloropyrimidine is a versatile halogenated pyrimidine derivative that serves as a critical building block in advanced organic synthesis. Its molecular structure, featuring both a benzyl-protected oxygen and reactive chlorine atoms, makes it an invaluable intermediate for constructing complex heterocyclic systems. This compound is primarily sought after by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and specialty materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of nucleoside analogs, kinase inhibitors, and other targeted therapeutic agents.
• Agrochemical Research: Building block for developing new herbicides, fungicides, and plant growth regulators with specific modes of action.
• Material Science: Used in the creation of specialty polymers, liquid crystals, and organic electronic materials.
• Chemical Biology: Serves as a probe or labeling reagent in biochemical research and assay development.
• Custom Synthesis: Employed by contract research and manufacturing organizations (CROs/CMOs) for client-specific molecule construction.
• Academic Research: Utilized in universities and institutes for methodological studies in heterocyclic and medicinal chemistry.

Basic Information

Product Name	5-(Benzyloxy)-2,4-Dichloropyrimidine
CAS No.	91183-17-4
Molecular Formula	C11H8Cl2N2O
Molecular Weight	255.10 g/mol
Synonyms	2,4-Dichloro-5-(phenylmethoxy)pyrimidine; 5-Benzyloxy-2,4-dichloropyrimidine; 2,4-Dichloro-5-benzyloxypyrimidine; 5-(Benzyloxy)-2,4-dichloro-pyrimidine; NSC 405122; 5-O-Benzyl-2,4-dichloropyrimidine; Pyrimidine, 2,4-dichloro-5-(phenylmethoxy)-
EINECS	Contact for details

Quality Control

Our 5-(Benzyloxy)-2,4-Dichloropyrimidine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your most demanding synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep the container tightly sealed when not in use to prevent moisture absorption and contamination. Store away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (GC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.