Description

N(Epsilon)-Acetimidoglucagon, Phe(1)- is a chemically modified peptide derivative of the glucagon hormone, specifically designed for advanced research and development. This compound is of significant value for its role in studying glucagon receptor interactions, metabolic pathways, and the development of novel therapeutic agents. It is primarily utilized by pharmaceutical R&D teams, academic research institutions, and biotechnology companies focused on endocrinology, diabetes research, and peptide-based drug discovery.

Application

• Pharmaceutical Research & Development: Serves as a key intermediate or reference standard in the synthesis and study of novel glucagon analogs and peptide therapeutics.
• Metabolic Disease Studies: Used in preclinical research to investigate glucagon signaling, hepatic glucose production, and potential treatments for diabetes and hypoglycemia.
• Biochemical Assay Development: Employed as a critical reagent in the development and validation of receptor binding assays (RBA) and other in vitro bioassays.
• Academic Research: Supports fundamental studies in endocrinology, peptide chemistry, and hormone-receptor interaction mechanisms at universities and research institutes.
• Quality Control & Analytical Reference: Functions as a high-purity certified reference material (CRM) for analytical methods like HPLC and LC-MS in quality control laboratories.

Basic Information

Product Name	N(Epsilon)-Acetimidoglucagon, Phe(1)-
CAS No.	91173-43-2
Molecular Formula	C153H225N43O49S
Molecular Weight	3485.7 g/mol
Synonyms	Acetimidoglucagon; Nε-Acetimidoglucagon; Glucagon, N6-(aminoiminomethyl)-; Phe1-Glucagon amide; [Phe1]-Glucagon; Glucagon (1-29), Nε-acetimido-; Glucagon analog; H-His-Ser-Gln-Gly-Thr-Phe-Thr-Ser-Asp-Tyr-Ser-Lys-Tyr-Leu-Asp-Ser-Arg-Arg-Ala-Gln-Asp-Phe-Val-Gln-Trp-Leu-Met-Asn-Thr-NH2 (acetimido-Lys); Research Peptide 91173-43-2
EINECS	Contact for details

Quality Control

Our N(Epsilon)-Acetimidoglucagon, Phe(1)- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, MS for identity confirmation, and amino acid analysis. A comprehensive Certificate of Analysis (COA) detailing purity, peptide content, and solvent residues is provided with every shipment to ensure compliance with research-grade standards.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a freezer. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to prevent condensation and moisture uptake.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95.0%
Peptide Content	≥ 80.0% (by weight)
Single Impurity (HPLC)	≤ 1.0%
Water Content (KF)	≤ 5.0%
Acetate Content (HPLC)	≤ 10.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.