Description

6-(2-Bromoethyl)-3,7-Dimethyl-5H-Thiazolo[3,2-A]Pyrimidin-5-One Monohydrobromide is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound is valued for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring sophisticated molecular architectures. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of new chemical entities and specialty fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of complex drug candidates, especially those containing fused thiazolopyrimidine cores.
• Organic Synthesis Building Block: Used in research-scale and process chemistry for constructing novel heterocyclic compounds due to its reactive bromoethyl and pyrimidinone functional groups.
• Medicinal Chemistry Research: Serves as a scaffold for structure-activity relationship (SAR) studies in drug discovery programs targeting various disease pathways.
• Chemical Reference Standard: Employed as an analytical standard for quality control and method development in pharmaceutical analysis.
• Specialty Fine Chemical Production: Integrated into the manufacturing of high-value, low-volume chemicals for agrochemical or material science applications.

Basic Information

Product Name	6-(2-Bromoethyl)-3,7-Dimethyl-5H-Thiazolo[3,2-A]Pyrimidin-5-One Monohydrobromide
CAS No.	91125-08-5
Molecular Formula	C10H12BrN3OS • HBr
Molecular Weight	380.10 g/mol
Synonyms	6-(2-Bromoethyl)-3,7-dimethyl-5H-thiazolo[3,2-a]pyrimidin-5-one hydrobromide; 5H-Thiazolo[3,2-a]pyrimidin-5-one, 6-(2-bromoethyl)-3,7-dihydro-, monohydrobromide; Thiazolo[3,2-a]pyrimidine derivative; 6-(2-Bromoethyl)-3,7-dimethylthiazolo[3,2-a]pyrimidin-5-one HBr salt
EINECS	Contact for details

Quality Control

Our 6-(2-Bromoethyl)-3,7-Dimethyl-5H-Thiazolo[3,2-A]Pyrimidin-5-One Monohydrobromide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and heavy metals, to ensure it meets the stringent requirements for pharmaceutical R&D and production. A detailed Certificate of Analysis (COA) is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.