Description

2-Amino-4-Phenylpyrimidine-5-Carboxylic Acid is a high-purity, functionalized pyrimidine derivative serving as a critical building block in advanced organic synthesis. Its value lies in its bifunctional structure, combining a reactive carboxylic acid group with an amino-substituted heterocyclic core, enabling the construction of complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, particularly in kinase inhibitor and antiviral research.
• Agrochemical Synthesis: Used in the production of advanced herbicides and fungicides that require specific pyrimidine-based scaffolds.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized chelating ligands in coordination chemistry and catalysis.
• Material Science Research: Employed in the synthesis of organic semiconductors and photoactive materials due to its electron-deficient aromatic system.
• Chemical Biology Probes: Utilized to create labeled compounds and molecular probes for studying biological mechanisms.
• Custom Synthesis & Contract Manufacturing: A fundamental starting material for custom synthesis projects requiring tailored pyrimidine carboxylic acids.

Basic Information

Product Name	2-Amino-4-Phenylpyrimidine-5-Carboxylic Acid
CAS No.	91093-42-4
Molecular Formula	C11H9N3O2
Molecular Weight	215.21 g/mol
Synonyms	4-Phenyl-2-aminopyrimidine-5-carboxylic acid; 5-Carboxy-2-amino-4-phenylpyrimidine; 2-Amino-4-phenyl-5-pyrimidinecarboxylic acid; 2-Amino-4-phenylpyrimidine-5-carboxylate; APPC Acid; 91093-42-4; 4-Phenyl-2-aminopyrimidine-5-carboxylate
EINECS	Contact for details

Quality Control

Our 2-Amino-4-Phenylpyrimidine-5-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets exacting standards for research and production. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to guarantee traceability and consistent quality.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). The compound may be hygroscopic (moisture-sensitive); keep the container tightly sealed when not in use to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.