Description

n-Acetyl-S-(4-Nitrophenyl)-L-Cysteine is a specialized biochemical derivative of the amino acid L-cysteine, featuring an acetyl-protected amine and a 4-nitrophenyl thioether group. This compound is a critical intermediate and reference standard in biochemical research and pharmaceutical development, particularly for studying enzyme activity and metabolic pathways. It is essential for researchers and manufacturers in the fields of analytical chemistry, toxicology, and drug discovery who require high-purity, well-characterized metabolites for method validation and biomarker studies.

Application

• Biochemical Research Standard: Serves as a certified reference material (CRM) for calibrating analytical instruments and validating methods in metabolite identification.
• Enzymology Studies: Used as a substrate or inhibitor in studies of cysteine-conjugating enzymes, such as glutathione S-transferases (GSTs).
• Toxicology & Metabolite Analysis: Acts as a key analytical standard for detecting and quantifying cysteine adducts formed from xenobiotic metabolism, crucial for safety assessments.
• Pharmaceutical Intermediate: Employed in the synthesis of more complex molecules for drug discovery programs targeting specific enzymatic pathways.
• Proteomics & Biomarker Development: Utilized in the development of assays to study protein modifications and identify potential disease biomarkers.

Basic Information

Product Name	n-Acetyl-S-(4-Nitrophenyl)-L-Cysteine
CAS No.	91088-55-0
Molecular Formula	C₁₁H₁₂N₂O₅S
Molecular Weight	284.29 g/mol
Synonyms	N-Acetyl-S-(4-nitrophenyl)cysteine; N-Acetyl-S-p-nitrophenyl-L-cysteine; S-(4-Nitrophenyl)-N-acetyl-L-cysteine; N-Acetyl-3-[(4-nitrophenyl)thio]-L-alanine; L-Cysteine, N-acetyl-S-(4-nitrophenyl)-; Acetyl-S-(p-nitrophenyl)cysteine; (2R)-2-Acetamido-3-(4-nitrophenyl)sulfanylpropanoic acid
EINECS	Contact for details

Quality Control

Every batch of n-Acetyl-S-(4-Nitrophenyl)-L-Cysteine is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure compliance with high-purity research standards. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccant or inert atmosphere conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm
Residue on Ignition	≤ 0.1%
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.