Description

4-Chloro-2-Methylsulfanyl-6-Phenylpyrimidine is a versatile pyrimidine-based heterocyclic building block of significant interest in advanced organic synthesis. Its core value lies in its bifunctional reactivity, featuring both a chloro and a methylthio leaving group, which makes it a critical intermediate for constructing complex molecular architectures. This compound is primarily sought by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of potential drug candidates, particularly kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides, leveraging its pyrimidine core.
• Material Science Research: Acts as a building block for creating novel organic electronic materials, ligands for catalysis, and specialty polymers.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological pathways and enzyme functions.
• Custom Synthesis & Contract Manufacturing: A fundamental starting material for custom synthesis projects and scale-up processes in fine chemical production.

Basic Information

Product Name	4-Chloro-2-Methylsulfanyl-6-Phenylpyrimidine
CAS No.	91063-60-4
Molecular Formula	C11H9ClN2S
Molecular Weight	236.72 g/mol
Synonyms	4-Chloro-2-(methylthio)-6-phenylpyrimidine; 2-(Methylthio)-4-chloro-6-phenylpyrimidine; 6-Phenyl-4-chloro-2-methylsulfanylpyrimidine; 4-Chloro-6-phenyl-2-(methylthio)pyrimidine; 4-Chloro-2-methylmercapto-6-phenylpyrimidine; 4-Chloro-2-methylthio-6-phenylpyrimidine; 91063-60-4; 4-Chloro-2-(methylsulfanyl)-6-phenylpyrimidine
EINECS	Contact for details

Quality Control

Our 4-Chloro-2-Methylsulfanyl-6-Phenylpyrimidine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment supports applications in GMP-intermediate and research-grade synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound is light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.