Description

5-(Benzyloxy)-4-Chloropyrimidine is a high-purity, functionalized pyrimidine derivative of significant interest in advanced organic synthesis. This compound matters as a versatile and critical building block for constructing complex molecular architectures, particularly in pharmaceutical research and development. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for kinase inhibitors and other targeted therapies.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and plant growth regulators.
• Ligand and Catalyst Development: Acts as a starting material for creating specialized ligands used in catalysis and material science.
• Nucleic Acid Chemistry: Employed in the modification and study of nucleosides and nucleotides for biochemical research.
• Chemical Biology Probes: Utilized to develop molecular probes for studying enzyme function and biological pathways.
• Custom Synthesis & Contract Manufacturing: A fundamental substrate for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) producing bespoke compounds for clients.

Basic Information

Product Name	5-(Benzyloxy)-4-Chloropyrimidine
CAS No.	91063-23-9
Molecular Formula	C11H9ClN2O
Molecular Weight	220.65 g/mol
Synonyms	4-Chloro-5-(phenylmethoxy)pyrimidine; 4-Chloro-5-benzyloxypyrimidine; 5-Benzyloxy-4-chloropyrimidine; 91063-23-9; 4-Chloro-5-(benzyloxy)pyrimidine; Pyrimidine, 4-chloro-5-(phenylmethoxy)-; 5-(Benzyloxy)-4-chloro-pyrimidine
EINECS	Contact for details

Quality Control

Our 5-(Benzyloxy)-4-Chloropyrimidine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specification results. Our quality commitment supports applications requiring high-purity intermediates under cGMP and ISO 9001 guidelines where applicable.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep the container sealed to protect this light-sensitive material from moisture and atmospheric contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.